Long-term treatment with transcranial pul... - Cure Parkinson's

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Long-term treatment with transcranial pulsed electromagnetic fields improves movement speed and elevates cerebrospinal erythropoietin 2021

Bolt_Upright profile image
37 Replies

Long-term treatment with transcranial pulsed electromagnetic fields improves movement speed and elevates cerebrospinal erythropoietin in Parkinson’s disease journals.plos.org/plosone/a...

"Conclusions

In patients with Parkinson’s disease, daily treatment with bipolar transcranial pulsed electromagnetic fields (T-PEMF) for three periods of eight weeks appeared to strengthen the natural protective/compensatory response in the human brain.

Motor performance in terms of movement speed was improved markedly compared to the natural progression seen in the PD-control group and CSF levels of erythropoietin increased in the T-PEMF group. Post treatment values of the STS completion time corresponded to the level of an age matched healthy reference group. These results suggest that T-PEMF has a neuro-restorative and/or a neuroprotective effect and that T-PEMF treatment is a potential innovative neuroprotective therapy in PD. However, the results do not exclude additional influence of other growth factor mechanisms."

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Bolt_Upright profile image
Bolt_Upright
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37 Replies
park_bear profile image
park_bear

Interesting. Unfortunately they did not describe their PEMF apparatus in sufficient detail to be able to reproduce it. Also, they did not use UPDRS to assess the result so we are not in a position to compare efficacy to other treatments.

Bolt_Upright profile image
Bolt_Upright in reply to park_bear

I found these details in the report. I am guessing Von could build one:

"The treatment was home-based, and each daily session lasted 30 min. T-PEMF was applied through seven coils placed in a helmet-like shape, with one coil in the central occipital region, one in each frontal-parietal region, and two bilaterally in the temporal region (anterior and posterior) (Re5 NTS Parkinson Treatment System, Re5, Frederiksberg, Denmark). The seven coils were connected to an external pulse generator that generated bipolar, squared pulses (±50 V, 3 ms, 50 Hz) to initiate rapid current changes in the coils, giving rise to rapidly changing, time-dependent electromagnetic fields. An electromagnetic field penetrates through electrically insulated tissue (e.g. the skull) and induces a driving force on charged particles and thereby electrical currents in the brain. The peak E-field intensity has been estimated to approximately 2.5 mV/cm near the coil [10], and the spatial distribution is highly dependent on the steep gradient of the applied bipolar pulsed electromagnetic field."

park_bear profile image
park_bear in reply to Bolt_Upright

I am an electrical engineer and I can build one myself. I already saw those details and they are not sufficient. To properly reproduce the field that is generated it is necessary to know the exact placement and diameter of the coils. The placement is best conveyed by an image. I could build something based on this description but it would not be the same as what they have done without knowing greater detail.

Bolt_Upright profile image
Bolt_Upright in reply to park_bear

I emailed Dr Jensen. Maybe they will provide some details.

rebtar profile image
rebtar in reply to Bolt_Upright

Did you get a response from Dr. Jensen?

Bolt_Upright profile image
Bolt_Upright in reply to rebtar

I did not get a response from Dr Jensen.

Bolt_Upright profile image
Bolt_Upright in reply to park_bear

I wonder if the God Helmet would help? god-helmet.com/wp/god-helme... I've always wanted one.

Bolt_Upright profile image
Bolt_Upright in reply to Bolt_Upright

Ah, TMS is a million times more powerful than the God Helmet: books.google.com/books?id=k...

kaypeeoh profile image
kaypeeoh

I just got the LIFTiD neurostimulation device. Haven't tried it yet.

Bolt_Upright profile image
Bolt_Upright in reply to kaypeeoh

getliftid.com/buy.html

MBAnderson profile image
MBAnderson in reply to kaypeeoh

keep us posted please

kaypeeoh profile image
kaypeeoh in reply to MBAnderson

Working on it now. At the same time I'm descaling the coffee machine and I'm trying to figure out why the speedometer doesn't work on my motorbike.

device
kaypeeoh profile image
kaypeeoh in reply to kaypeeoh

Only thing I noticed so far is the two neurosensers left 2 huge hickeys on my forehead but they seem to be fading. The strap was prolly too tight. Coffee is less bitter.

134A profile image
134A in reply to kaypeeoh

I’m going to wrap my PEMF auxiliary “spot” treatment pad around my head lol.

kaypeeoh profile image
kaypeeoh in reply to 134A

I was at a medical conference where a guy had set up a table to hawk PEMF devices. I mentioned that I had Achilles tendinopathy. He had me sit, take my shoe and sock off, and taped the device to my heel. Then he took off and I was stuck there for an hour. People kept walking by asking me questions, assuming I was the sales rep. It helped the pain but only for a couple of hours.

kaypeeoh profile image
kaypeeoh

I used the LIFTiD neurostimulation device again this morning. I didn't realize I'd put it on upside-down until it was already running. The pamphlet said never stop once it's running. So I left it on. So did I lose IQ points by putting it on bassackwards? BTW, the speedometer problem was a loose cable.

kaypeeoh profile image
kaypeeoh

Still using the LIFTiD neurostimulation device. I noticed a small electric shock under the left pad. But not the right. I checked the pamphlet but no answer. Eventually I remembered that....38 years ago a horse kicked me in the face, shattering my jaw. And damaged my right trigeminal nerve. OF the three nerve branches--lip, eye and temple--the temple branch never healed completely. So even now I'm still numb around the temple. My only joke: I'm literally a numb skull. I guess that explains why I don't feel an electric pulse under the right pad.

House2 profile image
House2 in reply to kaypeeoh

With direct current, not feeling the stimulation equally under the electrodes is normal, it is a cathode/anode thing.

jeanette2372 profile image
jeanette2372 in reply to kaypeeoh

I am very interested to hear whether you notice any results from using the LiftID.

kaypeeoh profile image
kaypeeoh in reply to jeanette2372

I don't have any physical symptoms, ie stiffness or balance problems. But cognitive function is a problem according to the neuro.

I do crosswords all day. 'Challenging Puzzles' take a lot longer to complete but I can get 70-90% completion on each one. The 70% completions aren't more difficult, I think they're written by a Brit. With a Brit's sense of humor.

A recurring clue is Whodunit Skeleton. It took me forever to realize the answer. But now it comes up regularly in these puzzles. So I don't know whether my cognitive function is improving or I'm simply remembering clues from previous puzzles.

I spent 9 years in college but my goal was being accepted to vet med school. So medical clues--leg bone?--are easy but they're a small number in a thousand-clue puzzle.

So I don't know whether my cognitive function is improving by working the puzzles. The literature says to do something that's mentally challenging while wearing the LIFTiD neurostimulation device. I do that with the puzzles.

The only other mental activity that I've tried might be learning Spanish. I took a year of Spanish years ago. So maybe continue with that? I dunno.

vv
Despe profile image
Despe in reply to kaypeeoh

Kay,

I have read and quite understand that learning a second language more than improves brain function. It is a very challenging and rewarding experience.

Bolt_Upright profile image
Bolt_Upright in reply to Despe

Before my RBD diagnosis I used to watch La Casa de Al Lado while riding my bike every day so I would learn Spanish (I did not). Catherine Siachoque looks like Kristen Wiig. It has a great opening: youtu.be/kb7TyEobv6Q

Bolt_Upright profile image
Bolt_Upright in reply to Bolt_Upright

It's on Hulu.

Despe profile image
Despe in reply to Bolt_Upright

Thanks, Bolt! I am not familiar with the program or the names.

I have met the second language challenge tough. :) English is not my native tongue. Started English, French and German when I was a teen. I only continued with English as that was/is the easiest language of the three.

kaypeeoh profile image
kaypeeoh in reply to Despe

I was born in Germany. Moved to the U.S. when I was 5 or so. Wasn't naturalized til age 15. So German was a cradle language. In college there was a group of Spanish girls, stunners all, who caught my attention. I thought taking Spanish might give me an edge. They were from Brazil.

Bolt_Upright profile image
Bolt_Upright in reply to kaypeeoh

Where they speak Portuguese?

kaypeeoh profile image
kaypeeoh in reply to Bolt_Upright

That's the joke. It sounds like Spanish...

Despe profile image
Despe in reply to kaypeeoh

Very interesting, Kay. Do you speak German? I was early twentys when I came to the US.

kaypeeoh profile image
kaypeeoh in reply to Despe

My first day in an American grammar school I was teased to death because of my accent. I was able to get rid of the accent quickly. I can communicate with my German mother but not much else. I took German in high school thinking it would be an easy 'A' but the teacher had a much different idea.

Despe profile image
Despe in reply to kaypeeoh

Don't blame her! :) I had difficulties with the long German words and their pronunciation.

On the other hand, you may try learning Greek. 😂

kaypeeoh profile image
kaypeeoh in reply to Despe

The teacher was a male who left Germany as Hitler was taking over. Because I was German he actually expected me to work. Silly man.

Despe profile image
Despe in reply to kaypeeoh

I know Germans are hard working and very disciplined. However, my mother lived during the German occupation and was telling us horror stories about German occupation and their atrocities.

kaypeeoh profile image
kaypeeoh in reply to Despe

I heard the same from my mother.

kaypeeoh profile image
kaypeeoh in reply to jeanette2372

I dunno, lately the crossword puzzles seem too easy. My wife found more from different publishers and so far they're no different.

Short video below states that in Europe it’s used for PD It’s used for cancer bc it decreases the growth of the cancer cells. If it decreases the growth of cancer cells, maybe there is a chance it can reduce protein aggregation? Or what would the target be? How is it treating depression? (I need to reread below most likely) What does it actually do that addresses the depression?

youtu.be/7nZ4u_MMFBM

This short clip is a young man with brain cancer who uses PEMF.

youtu.be/-sBvIB0xn7M

youtu.be/63HtmFgOCYE

In an interview, this doctor says he gives free consultations. I could do it but I lack the technical background to understand as much as many of you can drpawluk.com/

JayPwP profile image
JayPwP

I recently read 'erythropoietin' here:

healthunlocked.com/cure-par...

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