Alpha-synuclein, the culprit in Parkinson's Disease, is required for normal immune function.

"This study adds to the growing body of evidence that αS accumulates within the nervous system of individuals with PD as a result of an immune response. "

globenewswire.com/news-rele...

cell.com/cell-reports/fullt...

[Bolt_Upright]

May be evidence that PD is an autoimmune disease.

[Hanger112]

I wonder which will end up killing me. The disease, or the stuff in my body which kills the disease?!

[jeffreyn]

"The connection between neuronally derived αS and the eventual development of PD remains to be resolved."

Good progress, certainly, but not (yet) the major breakthrough that we need (IMHO).

I've been following Zasloff et al. since this AlzForum article came out in 2017:

Put ’Em Up: Does α-Synuclein Help Fight Microbes in the Gut?

alzforum.org/news/research-...

[jeffreyn in reply to jeffreyn]

Hopefully, the collaboration with NIH will spark more interest from other research groups.