Ubisol-Q10, a Nanomicellar & Water-Dispersible Formulation of Coenzyme-Q10 as a Potential Treatment for Alzheimer’s and Parkinson’s Disease

[Bolt_Upright]

Had not seen Ubisol-Q10. I could not find it for sale.

Ubisol-Q10, a Nanomicellar and Water-Dispersible Formulation of Coenzyme-Q10 as a Potential Treatment for Alzheimer’s and Parkinson’s Disease mdpi.com/2076-3921/10/5/764...

"Abstract

The world continues a desperate search for therapies that could bring hope and relief to millions suffering from progressive neurodegenerative diseases such as Alzheimer’s (AD) and Parkinson’s (PD). With oxidative stress thought to be a core stressor, interests have long been focused on applying redox therapies including coenzyme-Q10. Therapeutic use has failed to show efficacy in human clinical trials due to poor bioavailability of this lipophilic compound. A nanomicellar, water-dispersible formulation of coenzyme-Q10, Ubisol-Q10, has been developed by combining coenzyme-Q10 with an amphiphilic, self-emulsifying molecule of polyoxyethanyl α-tocopheryl sebacate (derivatized vitamin E). This discovery made possible, for the first time, a proper assessment of the true therapeutic value of coenzyme-Q10. Micromolar concentrations of Ubisol-Q10 show unprecedented neuroprotection against neurotoxin exposure in in vitro and in vivo models of neurodegeneration and was extremely effective when delivered either prior to, at the time of, and most significantly, post-neurotoxin exposure. These findings indicate a possible way forward for clinical development due to effective doses well within Federal Drug Administration guidelines. Ubisol-Q10 is a potent mobilizer of astroglia, antioxidant, senescence preventer, autophagy activator, anti-inflammatory, and mitochondrial stabilizer. Here we summarize the work with oil-soluble coenzyme-Q10, its limitations, and focus mainly on efficacy of water-soluble coenzyme-Q10 in neurodegeneration."

[akgirlsrock]

I'm using coq10 and glutathione both liposomanol quicksilver products from Chris Shade from Dr. Vitamin very reputable products. I wish I could afford his detox products, I thought these products would help my mitochondria. Only been using for a month, I'm wondering if anyone feels better after using for awhile.

[eschneid in reply to akgirlsrock]

Been taking between 1200 + 1600 mg Co Q10 since dx in 07. Cannot say that it definitely slowed my progression, but the first 12 years things did move pretty slow. For the past 3 years I have started to get whacked harder and quicker unfortunately. I still live for that good ON feeling so I can enjoy my life and will continue to fight the PD monster. Would be interested in trying Ubisol if anyone can find it. Thanks ⚡