Do Antibiotics cause Parkinson's Disease? - Cure Parkinson's
Do Antibiotics cause Parkinson's Disease?
This platform doesn't play nice with my cell phone.
I look for the point of origin and this is gut dysbiosis. Antibiotics destroy the balance between beneficial bacteria and harmful bacteria. Do you know what else does this? Glyphosate.
Antibiotics invented in 1928.Glyphosate introduced in 1974
James Parkinson wrote an essay on the shaking palsy in 1814
Go figure
I am pretty sure the incidence has increased substantially in recent years.
Oh sure. I'm not disputing that toxins may have contributed to an increase in PD (or toxin caused Parkinsonisms.)
But it's not the case that "antibiotics cause PD". All the PD before 1928 was NOT caused by antibiotics
The incidence has increased, and toxins, diet, lifestyle all contribute. But PD is largely a disease of old age, and people are living longer. The more modern medicine stops people dieing of cancer , heart disease and the like, the more they can hang around to get PD and Alzheimers
I am sure that you are aware that Parkinson’s does not start at the diagnosis date. PWP are almost certainly sick with the disease for at least 10 years before diagnosis.If we didn’t have such a rotten healthcare system, I would’ve been diagnosed when I was 50, and would recognize thatThe disease was at work for years before that. Does not sound like a disease of old age to me. When I complained of poor sleep and gastrointestinal symptoms in my 40s, I was labeled a hypochondriac and offered a prescription for Prozac. When I suggested to one primary care physician that I might have anxiety disorder he suggested I get a new doctor.
By the way, and I don’t know what it was like in the UK, doctors here in the US in the late1990s and early 2000s went on a maniacal orgy of prescribing SSRI medications like Prozac. Investigative reporting by ProPublica, an arm of national public radio, revealed that Pharma companies were using every tactic within their means, legal and illegal, to push these drugs, The damage to the health and well-being of the unsuspecting public is almost certainly incalculable. When your doctor is a stooge for big corporate interests, you have to wonder how are your Health is getting short changed. Then, right on the heels of that mess we were served up the opioid crisis. This is why I will never believe that the process for approving the Covid vaccine has been anything more than an extension of the blatant criminality that preceded it. I also believe that progress in finding a cure for Parkinson’s is hostage to similar corruption.
Could not love this more!
Lovely. Enjoy your day
I disagree. PD is no longer A disease of old age....and our life expectancy just declined. Please see my reply to your earlier comment.
SE
I started reading but it's drivel. If you fix something that ain't broke you won’t achieve anything. Please rant somewhere else
Gut dysbiosis, nutritional deficiencies and toxic chemicals certainly existed in 1814, when the shaking palsy was first described. No doubt the shaking palsy existed long before it was described too.
The cause of gut dysbiosis (over use and misuse of antibiotics - Glyphosate is a patented antibiotic) nutritional deficiencies (processed foods, sugar is an anti-nutrient) and the over use and misuse of pesticides in food production (Roundup is the most used pesticide in the world bar none) along with the explosion in untested and unregulated chemicals (PFOS anyone) is fueling a pandemic of neurodegenerative disorders. [I understand that my examples are narrow and that there is no single cause of ND disorders.]
Is this research being funded? Hell no, why would they kill the golden goose that is funding the industrial/medical and political complex? No one wants to cure this, there's no money in it unless you can find a drug to ease the symptoms and patent it. L/C is long off patent and along comes Rytary.
As a group of people directly or indirectly impacted by neurological disorders - what have we got to lose by trying to heal ourselves from what is clearly an environmental injury?
The underlying disease process is the same, the variables are genetics, some people are more vulnerable than others to toxins, the type of toxin and the route of exposure.
My mother died with PD, I have an atypical form of ALS, called ALS plus syndrome aka Parkinsonism. At the end of her life my mother's PD looked more like ALS (or at least MSA). Increasingly I am coming across research that lumps PD, AD and ALS together - they are not unrelated. They can and do occur together. This is our wake up call to action.
There are about 100 documented cases of ALS reversals. Terry Wahls, MD recovered from her MS. The treatment for PD is not in a pill. Heal your gut - heal your brain.
SE
*I'm replying to your comment directly but think it needs a wider audience- that's why you see it twice in my post.
99% of doctors have absolutely no clue about healing the gut because there’s no product from Pharma that they can prescribe. One of the most interesting things I’ve read on the gut microbiome came out over 15 years ago and it was this. Researchers in one study noticed that when they wiped out a test subject’s microbiome with strong antibiotics for the purpose of this particular trial, they noticed that people recover their micro biome at vastly different rates. Some people had their full complement of microbes back in a couple weeks, others lost substantial types and numbers of their microbes and were unable to recover back to a normal state even after something like six months or a year.
That is interesting.
Makes me think of a book on sheep that compares the inside of the small intestine of nursing lambs raised on pasture to those confined to a pen. The lambs on pasture have access to grass and various other plants (even though they are nursing and too young to survive on pasture), and their small intestine was well-developed with large folds and plentiful villi -- vastly superior to the lambs confined to a shed. The picture was very dramatic; I wish I could find it to post a copy here.
The video link I posted yesterday, with Dr. Mischley's clarification about her stance on probiotics, she mentions that she prefers to have food provide the material for the 'right bugs' to flourish. She mentions buckwheat, sorghum, farro, and quinoa although I've no idea why those were specifically part of her PRO-PD questionnaire.
Perhaps the difference in that trial you mentioned is due to some participants having a more varied diet which encourages a more varied biota?
In the US, our food supply has become a dumping ground for ag by products. There is, for instance, GMO corn, grown with heavy use of glyphosate, in just about everything.
It wouldn't surprise me if the research didn't take diet into consideration.
Kampavata/ Vepathu (Parkinson's) documented in ayurvedic medicine for 3,500 years. Similar to how smallpox innoculation goes back to 1500 or earlier in the non-western world. We do love to appropriate!
From the link:
"The short answer is 'NO'”
The actual study:
pubmed.ncbi.nlm.nih.gov/317...
" PD patients had purchased more antibiotic courses than controls (6.32 vs. 6.25; P = 0.021),"
A textbook example of a difference that is statistically significant but not clinically meaningful - The average difference in number of courses of antibiotics between Parkinson's and non-Parkinson's patients was .07. In other words, if you took a group of 14 patients each from the Parkinson's and non-Parkinson's groups, the non-Parkinson's patients on average would have had a total of 87 prescriptions ( 6.25 X 14 ) among them over the study period, whereas the Parkinson's patients would have had 88 prescriptions.
They sliced and diced the data into over 30 subgroups. In only one of these subgroups did they find an odds ratio noticeably different than unity: 1.371 for 5 or more courses of Macrolides & lincosamides. In this case we have to ask whether it was use of antibiotics, or an underlying condition that caused this use of antibiotics, or merely random variation among 30 subgroups that was responsible for this result.
The long answer - NO
Thanks for breaking it down. I understand that correlation doesn't imply causation. Do you think gut dysbiosis plays a role in neurodegenerative illnesses?
This seems to be the general opinion. I have not taken it upon myself personally to assess the evidence.
As the article states, PD is a multifactorial disease and antibiotics use does not lead to PD invariably. However, any factor (including toxins, bad eating habits, environmental, etc) that leads to disturbance of gut microbiota and dysbiosis could trigger pro-inflammatory status, and that certainly could elevate the risk of developing PD for the vulnerable, whether that be genetic, age, lifestyle, etc. As a person who has been hurt by the fluoroquinolone class of antibiotics, I see this as an absolute possibility while the antibiotics are strongly associated with cellular toxicity and neurological side effects.
"While their therapeutic efficacy is clearly recognized and valuable for severe life-threatening infections, it is now evident that FQs are accompanied by a variety of systemic side effects, including common (gastrointestinal disturbances, headaches, skin rash, allergic reactions and others) and uncommon side effects [7]. These include QT prolongation [8], seizures [9], hallucinations [10], depression and anxiety [10], peripheral neuropathy [11], tendon rupture [12,13] and others. While the common side effects tend to disappear shortly after the treatment, the rare side effects seem to affect patients for longer, potentially their entire lifetime. Due to these side effects, the Federal Drug Agency (FDA) has released a statement in 2016 warning healthcare providers of the possibility of a “Fluoroquinolones associated disability” (FQAD) or “Fluoroquinolones toxicity syndrome” [14], which patients colloquially refer to as “being Floxed...
Despite the FDA proposing the existence of FQAD, this disease has yet to be formally recognized by healthcare systems worldwide. To date, there is still a degree of dismissal of FQAD-affected patients by healthcare providers and physicians.”
"Since there is sufficient evidence to suggest that GABA transmission is hindered by FQs, it is reasonable to postulate that the vagal circuit could be compromised at the NTS-DMV synapse after FQ use, possibly leading to the development of permanent GI disorders in FQAD."
I was given levaquin prior to surgery for a suspected bladder infection that I didn't have, my ALS accelerated afterwards. In an ALS group, people report developing ALS after surgery. We don't really know what the effects of the drugs are - I don't take anything now before researching it.
From the review - "Indeed, about 6.3 million FQs prescriptions were written for urinary tract infections (UTI), and about 1.6 million prescriptions were written for bronchitis and the common cold, for which FQs should not have been selected for treatment [2]. Even more concerning is that in addition to these aforementioned cases, 5.1% of adult ambulatory FQ prescriptions were issued for conditions that did not require antibiotics at all [2]. Even though the Infectious Diseases Society of America (IDSA) advises avoiding FQs for uncomplicated urinary tract infections [15], FQs were still prescribed in 40% of cases compared to other antibiotics including penicillins, urinary anti-infectives, and tetracyclines [2]."
What you experienced is unfortunately too prevalent...
Oh maaannnn. I was given it for UTI and had a serious adverse reaction with first pill. Pharmacist said not to ever take it again. It's upsetting that our lives are just tossed about so carelessly.
You were lucky to have stopped at 1 pill. Others are not so lucky and many don't even make the association until the lasting damages are done. FQs are powerfully effective for infections and caused negligent prescription abuse while the manufacturers intentionally downplayed serious side effects.
Yup. Doesn't instill confidence... or trust.
Gut dysbiosis, nutritional deficiencies and toxic chemicals certainly existed in 1814, when the shaking palsy was first described. No doubt the shaking palsy existed long before it was described too.
The cause of gut dysbiosis (over use and misuse of antibiotics - Glyphosate is a patented antibiotic) nutritional deficiencies (processed foods, sugar is an anti-nutrient) and the over use and misuse of pesticides in food production (Roundup is the most used pesticide in the world bar none) along with the explosion in untested and unregulated chemicals (PFOS) is fueling a pandemic of neurodegenerative disorders. [I understand that my examples are narrow and that there is no single cause of ND disorders.]
Is this research being funded? Hell no, why would they kill the golden goose that is funding the industrial/medical and political complex? No one wants to cure this, there's no money in it unless you can find a drug to ease the symptoms and patent it. L/C is long off patent and along comes Rytary.
As a group of people directly or indirectly impacted by neurological disorders - what have we got to lose by trying to heal ourselves from what is clearly an environmental injury?
The underlying disease process is the same, the variables are genetics, some people are more vulnerable than others to toxins, the type of toxin(s) and the route of exposure.
My mother died with PD, I have an atypical form of ALS, called ALS plus syndrome aka Parkinsonism. At the end of her life my mother's PD looked more like ALS (or at least MSA). Increasingly I am coming across research that lumps PD, AD and ALS together - they are not unrelated. They can and do occur together. This is our wake up call to action.
There are about 100 documented cases of ALS reversals. Terry Wahls, MD recovered from her MS. The treatment for PD is not in a pill. Heal your gut - heal your brain.
SE
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