Just found out about SAK3 and did not see anything posted here about it:
Single Administration of the T-Type Calcium Channel Enhancer SAK3 Reduces Oxidative Stress and Improves Cognition in Olfactory Bulbectomized Mice - Jan 2021 ncbi.nlm.nih.gov/pmc/articl...
In the present study, we observed that SAK3 ameliorated oxidative damage in the OBX mice brains. Moreover, we also discovered that SAK3 could play an important role in restoring cognitive impairments. In this way, we propose that SAK3 acts competitively to rescue AD pathogenesis, benefiting from its efforts to suppress oxidative stress.