I’m looking for recommendations to manage chronic fatigue and narcolepsy.

[marnegro]

During the past 3 years I have been consistently reducing weights in the gym along with increased fatigue and weakness. I have noted this seems to be related to the intake of levodopa, because at evening/ night when not medicated I feel alert and more strength but then suffer insomnia. I’m on my 15 years with PD.

[chartist]

Dr. Costantini had some success using HDT for diseases that had fatigue as a major symptom, well at least in terms of ameliorating the fatigue aspect.

pubmed.ncbi.nlm.nih.gov/233...

Aside from that, you might give consideration to Acetyl L Carnitine (ALC or ALCAR).

pubmed.ncbi.nlm.nih.gov/176...

pubmed.ncbi.nlm.nih.gov/147...

vitacost.com/productsearch....

If you are weight lifting, the ALCAR may be beneficial there, as you probably already know, for getting the most build out of your lifting.

Art

[marnegro in reply to chartist]

Thanks Art. Your knowledge and comments are always very appreciated.

[felixned]

If you take ld agonists (Pramipexole for example) talk to your neurologist asap

[marnegro in reply to felixned]

I’m just taking Sinemet and mucuna. I quit pramipexole and other dopamine agonist few years ago, but I’m curious to know what’s your concern. Thanks!

[felixned in reply to marnegro]

I used to take Pramipexole and it gave me the symptoms you mentioned plus an awful edema of the legs . I found that getting 5 or 6 hours of sleep at night (melatonin really helps) and solving digestive issues helps to keep your mind happy.

[park_bear]

I require levodopa specifically for sleeping and can make do with less during the day. I suggest trying the same - an extended release formulation of levodopa for night time, and a bit less than your current dosage during the day. Of course consult your doctor and get permission for any medication changes.

[marnegro in reply to park_bear]

Thanks Park Bear. I’ll certainly evaluate your recommendations.