Eliminate the off time.

[Don_oregon_duck]

Well this worked for me testing it over the last 13 months. It's a simple solution.

At the end of January 2020 I moved into an assisted living facility. Necessated more from my neuropathy than pd. I chose to have my meds dispensed to me by the, which they did always with in fifteen minutes of the scheduled time, ALWAYS. From January 2020 until March 2021 I had no cd/ld off periods. I had been having an off period 2-3 times a week. I started thinnking about it half way thru the year quietly. I wonder if I can make full year without an off period. I am presently starting my fourteenth month without a down period. I believe that taking cd/ld at the prescribed time without fail elimated my down times.

For those of you who want to ask questions I will give you all my answers now. I am am taking Ritary a sustained release cd/ld. I added some B-6 and B-12 about seven months in. I am taking 3 grams of B-1 daily. Other then that I changed nothing else the entire year. I suggest you try this before asking your questions. You already have my answers.

Don

[Hidden]

Rytary? What size dose and how many times a day?

[OREOLU]

Hi, I also take Rytary and have often thought about this that the inability to take cd/LD at the same time everyday usually cause the off periods. I concur with you Don.

[chartist]

Hi Don!

Good to see a post from you again! I haven't seen any posts from you in some time.

What are you using for the PN and what are your symptoms like?

Art

[jimcaster]

Hi, Don! I am DELIGHTED to hear from you, especially because you have good news! Thank you for befriending me when I was a newbie. 😊

[JayPwP]

B6 and B12, What time and dosage?

[TL500]

Hi Don, Thanks for your info.

Did your down time disappear before started taking B1, B6 and B12?

How long have you been taking meds cd/ld?

What do you mean by with in 15 minutes of scheduled time? eg. scheduled time is 8am, take it at 7.45am?

How far apart are your cd/ld?

Do you take B1, B6 and B12 at the same time and close to medication?

Is it possible you share your schedule of meds & supplements (B1 ,B6, B12 etc.) listing times please?

I have down time with every kinson tab wearing out, that is 3 times per day. I take meds about half an hour before starting exercise class or activities or shops. This is why I can't stick to same time everyday.

Thanks.

[richardo123]

You are exactly right . My wife had v o n nurses come into our home and give me meds same time every day that she worked. Result was less off times . Not complete like you but certainly BQL (better quality life. Have an awesome on time day .

[LeharLover62]

I wonder if the High Dose Thiamine might also play a role here? I noticed my husband’s off times, while not eliminated, were significantly better and milder after starting thiamine. (He’s now also effectively eliminated his by taking mannitol.)

[Smittybear7 in reply to LeharLover62]

How much mannitol does he take and how does he take it?