Is anyone else participating in this genetic study? I just joined and am urging my siblings and daughter to do it too. The earlier they can detect markers for PD the sooner they may find some way to combat it before all the neurons are destroyed. The test kit and follow up are free to you.
"For more information on how The Michael J. Fox Foundation and 23andMe are collaborating to speed Parkinson's genetic research, visit michaeljfox.org or 23andme.com/PD."
This reminds me of the article that park_bear posted on the recent thread. healthunlocked.com/parkinso...
"However, there is a lot the neuroscience field could learn from oncology. In recent years, cancer research has significantly benefited from studying the underlying genetics of the disease and from stratifying patients with the same type of cancer into subgroups with common characteristics.
“The major difference is that if you just look at the sheer number of publications in oncology compared to neurodegeneration, it’s probably tenfold higher. That is a direct correlation with success – an increase in understanding,”
“A few years ago, oncology was also having a lot of failures. That breakthrough in terms of harvesting the immune system is what’s led the major successes. I think we will start to see some of that in the neurodegeneration field – harnessing the immune system.”
labiotech.eu/brain/neurosci...
If we don't understand what contributes to the core of the problem along with finding the biomarkers to correlate/measure, we're at a loss.
This is the right direction to focus on in order to advance in neuroscience.
I must applaud MJF foundation for jump-starting this.
Lets see more of our community participating.
This video had been posted before but MJF comments on the 3:00 mark.
"We're zoning-in on what are the precursors to Parkinson's, who's gonna get it before they get it"
Good on you ladya2020
I had a 23and Me test about 2009. It was the brain child of Sergey Brin (google founder) and his then partner (owner of 23and Me). MJ F is a recent partner.
Currently at 23andMe has whole-genome genotype data for 5,449 Parkinson’s disease (PD) patients and 110,853 healthy subjects. This is by far the largest cohort of case-control samples in the world and a tremendous resource for research in PD. The objective is to perform detailed analysis of this data to further clarify the role of genetics in PD.
Research so far has already uncovered nearly twenty genes that regulate risk for the development of PD, An over view of genetic risk in PD will, in the future, allow for an earlier and more accurate diagnosis and, eventually, individually targeted treatment approaches.
Yes, I participated early on. My results were negative for the two most common mutations that they were screening for. This doesn’t rule out genetic causation; I was told there are other less commonly occurring mutations that could be responsible for PD.
Same here.
I don't know where you all are coming from, nationally, but I do know Canadians can not sign up due to something to do with our privacy rules VS the Yanks laws on privacy...
After I queried why I was rejected, the MJFF put a tag on sign-up and if your email is from Canada you will get the Too Bad So Sad message, I randomly try when I get another invite, so they may change parts of the Patriot Act.
I'm surprises me that there are only 5,449 PwP
I am surprised by this low number, also. The original goal was 10,000 (if I am remembering correctly) that’s why they made it free for PWP. I thought they had gotten closer to 10,000.
Yes Julie you and Sapeye are right, it does seem low number of pwp. I wonder if it is because it says whole genome, (I don’t understand implications) or if they made a mistake. This is the source.
michaeljfox.org/grant/using...
The number of pwp tested at 23aand Me is well over 10 ,000 now.
I did 23andme back in 2016. Negative for the two mutations. I just did the PD GENEration trial which tests for 5 mutations, all came out negative. You do the trial just like 23andme, from your home. parkinson.org/PDGENEration
I contacted them hoping Canadians could participate. Here's what they said:
Thank you for your interest in PD GENEration! Currently, we can only offer genetic testing to residents of the Unites States. However, we are working on making PD GENEration available in Toronto in Ontario, Canada in the next two months. Please visit our website for future updates, the link is below:
If you have any further questions, please don't hesitate to reach out to us.
Sincerely,
PD GENEration Team
I also did the 23 and me and came up negative for the genetic markers.
also did it, also negative
but I do have both "The longevity gene and the happyness gene" which apparently means I will live until at least 90. Not good
I also did 23 and me and was negative for both genetic markers.
I was negative for the genetic markers too.
What could be the cause of restless leg syndrome
Too much C/L
Recording available for NSB4PD webinar with Dr. Sackner-Bernstein on "Why I am optimistic that we might now have a Silver Bullet for PD"
