DNL151. LRRK2

[Parsa]

Denali therapeutics announces decision to advance DNL151 into late stage clinical studies in Parkinson’s patients

Do you guys have any info re this? Anyone engaged in trial?

[jeffreyn]

There was a PNT article about DNL151 about a month ago:

parkinsonsnewstoday.com/201...

[jeffreyn in reply to jeffreyn]

... and a Denali/Biogen DNL151 article about two months ago:

parkinsonsnewstoday.com/202...

[Parsa in reply to jeffreyn]

Thanks for sharing. I wanted to see if anyone is part of this. Do you know anyone?

[jeffreyn in reply to Parsa]

No. Not yet.

[Sapeye2020]

Did you read this announcement?

Denali, Biogen Partner to Move DNL151 Into Late-stage Parkinson’s Trials

August, 10, 2020

[LRRK2PD]

I considered trying to get involved but got scared by the two required spinal punctures. Also, they said that even if I were lucky enough to get the real drug (versus the placebo) and even if I had a very good response, I would have to stop when the study ended and would lose the benefit. Is that how all clinical trials work?