On and Off periods

[bigl62]

I take c/l but don't experience an "on or off" periods. What does that mean?

[Enidah]

What kind of meds are you taking and when were you diagnosed? I didn't have any on off for the first few years.

[bigl62 in reply to Enidah]

Nov 2016 C_/ L

[Juliegrace]

That is a good thing as long as the c/l is helping you. It may change in the future, it did for me as time and PD has gone on.

[grower]

That's an interesting question, I don't either, but at 6+years since diagnosis I'm just starting to feel like I need another one just before I take it so I guess it's coming. It seems to depend on the severity of your symptoms but some folk "run out" of the benefits of the extra dopamine in the c/l before it's time for another and so have "off" times.

[ekw513]

That means you should be very happy that your meds are working

[bigl62]

What I mean by no On is no symptom releaf. Iam always Off no matter how much medicine I take

[gwendolinej]

Hi there, my husband was initially diagnosed with LBD (Lewy BodyDementia) in 2012 and put on Madapar levadopa). It seemed to have no effect. The neurologist then added the Neupro patch. Within a few weeks, the change was so great, his diagnosis was changed to Parkinson's.

The neurologist ( through the Movement Disorder Clinic he was attending here in Australia) then measured the effect of the levadopa on him, using the PKG watch, which measures the effect immediately after taking the medication. In my husband's case, it showed a small change, which only lasted for a short time . My husband, like you, felt nothing.

[Somic67]

You mean that L/C meds are NOT effective for you? Then Why do you take them?

what happend if you stop L/C meds? No change or what?

My personal opinion is that L/C cronically depletes various substances necessary for the CNS to work well. Inspired by Doc Hintz works, I think to a sort of storage - (dopamine, vit B6 first) that is depleted pregressively until it is empty and when meds are gone your body cant compensate any more and you simply go out of beer. this takes time to go to zero depending on meds, age, nutrition, supplements, etc

[bigl62 in reply to Somic67]

If I don't take c/l my freezing and loss of words get a little worse