Subtle Differences In Brain Cells Hint at Why Many Drugs Help Mice But Not People
Heard this story on NPR this AM
Subtle Differences In Brain Cells Hint at Why Many Drugs Help Mice But Not People
Heard this story on NPR this AM
There is a very basic reason why most mouse brain studies are very poor predictors of what will help humans with Parkinson's: they check whether a substance will protect the mouse against an artificially induced form of parkinsonism. This quite a bit different from whether a substance will help a human, or even a mouse, recover from Parkinson's.
Right, pb. Some illnesses can be treated without knowing what is causing them and mechanism behind their progression. PD obviously doesn't belong to that kind. I am afraid we'll be stuck with palliative treatment until we understand the etiology of the disease, and understand what really is driving its progression.