Any NAC users out there ?

[KERRINGTON]

Is anyone using NAC, and if so, for how long, what brand, and have you noticed any improvement, problems etc. Thanks in advance !

[park_bear]

Yes I take NAC. About 600 mg twice a day. I compound my own – I add 25% by weight calcium hydroxide to neutralize the acidity, and encapsulate that mix in 00 capsules. This is not necessary for most people – it suffices to just buy NAC in capsules already.

I am not sure it has done anything for my Parkinson's, but it has been a lifesaver relieving prostate inflammation.

[KERRINGTON in reply to park_bear]

Well, if it helps one part of the body with inflammation, it should help other parts too ?

[park_bear in reply to KERRINGTON]

Maybe so. It is a very interesting compound in that it has many uses. Is FDA approved in IV form to remedy liver toxicity. It is also thins mucus and breaks up bacterial biofilms. I use it in pH neutralized form as part of my own customized toothpaste because it breaks up biofilms. That put a stop to dental decay I was having. My dentist says I am "smarter than the average bear".

[marieboyd in reply to park_bear]

What does your specialised toothpasrte consist of

[park_bear in reply to marieboyd]

pH neutralized NAC, calcium ascorbate, serrepeptase, all preserved in 40% ethyl alcohol.

[reedboat2 in reply to park_bear]

interesting toothpaste formula Park Bear, can you elucidate why you are using the enzyme serrepeptase?

[park_bear in reply to reedboat2]

It breaksup biofilms like NAC does. Biofilms cause tooth decay.

[AmyLindy in reply to park_bear]

Is it necessary/ Do u brush a long while and hold /swish to get a good coating?

[park_bear in reply to AmyLindy]

I regard the serrepeptase as optional but I have not tried to do without it. I use a Braun motorized brush for 2 minutes and then floss before rinsing.

[AmyLindy in reply to park_bear]

Good discipline #respect

[park_bear in reply to AmyLindy]

Diligently flossing daily after brushing (instead of when I get around to it) is a recent commitment because it seems my gums need it. It remains to be seen how well I honor this commitment. #fessing_up

[Hidden]

I take NAC everyday to help control my blood pressure. No problems to report after years of use.

Art

[KERRINGTON in reply to Hidden]

BP ? I'll have to look into that for my husband !

[Hidden in reply to KERRINGTON]

You have to take it with a NO agonist such as arginine for the reduced blood pressure effect. I read about it many years ago in a study. I did better than the study participants, but I also took a higher dose than the study.

care.diabetesjournals.org/c...

Notice the other benefits associated with this combination!

Art

[KERRINGTON in reply to Hidden]

Hmm, interesting. He tried arginine alone because we read that was good for bp, but the bp went up so he stopped. Now, we'll read up on the info you gave us. Thanks

[Astra7]

I take it every day. Just 500mg a day now as I got tired of taking so many pills. I’ve taken it since diagnosis and so far I’m not really declining though I do sometimes feel twitchy and I drag my left foot a little more.

I also take mannitol, azilect and a little madapor.

My neuro told me last time that my PD was not noticeable to the untrained eye.

[KERRINGTON in reply to Astra7]

Well, if you're not declining, then some of those 2 zillion pills gotta be working !

[Astra7 in reply to KERRINGTON]

I hope so!

[KERRINGTON in reply to Astra7]

Me too !

[SELFMeder]

I am mimicing the Phase 3 NAC Trial being orchestrated by Havard Med/Mass General

I take 800mg of NAC 2xDay, plus 1 to 2 NAC Infusions per month.

Awaiting results from Harvard trial...

[Astra7 in reply to SELFMeder]

How do you feel?

[KERRINGTON in reply to SELFMeder]

Hi, have you rec'd results from Mass Gen yet ?

[SELFMeder]

Heard fm my Neuro that the Inosine trials were not successful. No word yet on the NAC trials.

[KERRINGTON in reply to SELFMeder]

Any info yet on the NAC trials at Harvard Med/Mass Gen ?

[SELFMeder in reply to KERRINGTON]

Sorry. I may have confused that the early NAC trials were sponsored by Mass Gen. I was micmicking on my own another Trial there focusing on Inosine, which eventually turned out this year to be negative.

But very positive NAC results from small-sample trials at Thomas Jefferson University were published in Clinical Pharmacology & Therapeutics this year. NAC has also been recommended to me by Dr. Glen Rothfeld, who has PD and practices integrative medicine at Rothfeld Apothecary in Waltham, Massachusetts. Enough to encourage me to keep taking a large daily dose (2400mg) of NAC.

[KERRINGTON in reply to SELFMeder]

Thanks, I recently read about that study, but it involve both oral, and parental administration of Nac. I've been looking for more studies on it. One poster said the Hinz protocol uses it, while another says Dr Mischley doesn't use it now.

[SELFMeder]

Take a lk at the recent results for Zishenpingchan. Lg double blind study in China. Pretty definitive. Recorded no side effects.

[SELFMeder]

Ck out NAC. A couple of small studies found very positive results in reduction of typical PD symptoms. Recommended by Glen Rothfeld, an integrative MD located in Waltham, Massachusetts, who has had PD for many years.

[KERRINGTON]

Ha !I have been checking it over, and over.. actually taking it, till I read enough articles that said it needs to be injected in order to get into the brain... Sooo....figured I'd take a break, and do more searches. I like that Dr Rothfeld thinks enough of it to recommend it. ..a rare doctor. Can you share anything else he recommends ? Thanks.

PS--Check out Chartist for his and Elliot Green's views on Glutathione and NAC.