Ibuprofen

[saraoutwest]

The strangest thing has happened. For the past 10 days I’ve been in terrible pain with my shoulder and X-ray showed calific tendonitis. I have been taking ibuprofen and paracetamol round the clock just to keep on top of the excruciating pain. I’ve noticed in the past week though my PD symptoms have significantly diminished. I’m tremor dominant and still have tremor but much less troublesome. My agitation gone, my balance better, my woosy brain fog gone, gait better. Yesterday I didn’t even take senemit. I’m also on b1 2gms a day. Could it be related to ibuprofen use?

[Hidden]

I have read of lower occurences of Parkinson's with those that have history over years of daily ibuprofen

[Hidden]

Every improvement you mentioned has been reported by people taking B-1, but not by people taking ibuprofen. How long have you been on B-1 and have you found your optimal dose yet?

Art

[saraoutwest in reply to Hidden]

I have been taking b1 for around 3-4 mths at 4grm and do feel much improved especially with less agitation and nervousness. Yes, maybe it’s the b1. I recently dropped my dose from 3 to 2 gems per day. (In last week)

[jeffreyn]

Be careful with long-term use of ibuprofen. Have a read of this comment by Simon in an SoPD blog post from earlier this year.

scienceofparkinsons.com/201...

[Despe]

I have read that a lot of people with PD take ibuprofen daily as it's anti-inflammatory. PD is caused by inflammation so it is supposed to halt the progression.

[glenandgerry]

For how long have you been taking the B1? My husband has been taking it since April this year & he's been suffering with tremendous back pain (also since April) travelling down through his hip, thigh, calf and into his foot. He's taking the opiate tramadol & is on morphine. 3 weeks ago he had a series of spinal injections for spinal stenosis but they didn't make any difference whatsoever - he still has the pain.

I am beginning to wonder if the pain is related to the B1. I am going to stop giving it to him for a week and monitor his pain level to see if there's any improvement.

[Hidden in reply to glenandgerry]

Gerry,

Please let Dr. C know about Glen's back pain and medication he is taking for it and your plan to discontinue B-1 for a week so he can be up to date on Glen's situation.

Art

[glenandgerry in reply to Hidden]

I have not communicated with Dr C previously but will do so now as you suggest. Thanks Art for all your help.

[bassofspades in reply to glenandgerry]

I get similar pain symptoms. I'll write dr Costantini.

[glenandgerry in reply to bassofspades]

Please let us know what he has to say. Thanks.

[bassofspades in reply to glenandgerry]

Will do

[bassofspades in reply to glenandgerry]

I asked dr Costantini if back and leg pain, spam and muscle tension were a side effect of thiamine. He says...

Yes, when the dose is slightly excessive compared to the needs of the patient

[glenandgerry in reply to bassofspades]

Thanks Bass. Glen is not taking any B1 right now. I'm going to start introducing it again next week at a lower dose.

[bassofspades in reply to glenandgerry]

Im going to take a week off from b1 too, then start back up at a slightly lower dose.

[Blue-jeans]

Don't know but good for you! It could be that the pain was stressing you, now the pain has gone you are not stressed?? I'm guessing, but will ask you to take care of your stomach Brufen can be harsh.

[Getz]

I'm new here and have had an email update under this post saying Hi Getz .... but I can't find any link to it. Am I looking in the wrong place or has this message been deleted? I do respond to every inquiry mentioning me but if I can't find it I don't know what its about.

[felixned]

Continuous use of ibuprofen can damage your kidneys and also increase chances of a heart attack:

en.wikipedia.org/wiki/Ibupr...

[Kwinholt]

Hi . I am an ultra runner with PD and hace taken Ibuprofen everyday for years even before diagnosis. I wish I could say it kept the disease away. I helps with the pain , I can say that. I haven’t been on this forum for a bit , there was some negativity that kept me away for a while. I’ve been having a rough time lately being motivated with my running and just plain being positive about life. Along with dealing with my PD, I am dealing with a husband who is an alcoholic. We have been married for 36 years and always have each other’s back . I know he loves me but I can’t count on him any more and honestly that scares me. I have enough anxiety in social settings with my PD and adding in trying not to micro manage my husbands alcohol. We always had fun together doing and going places . Not so much anymore and I miss that terribly . Sorry for being a Debbie Downer . Sometimes just saying it out loud makes me feel better because I hold a lot in. Thanks for letting me vent my PD friends . Karen

[Juliegrace in reply to Kwinholt]

That's rough. Sorry the negativity kept you away. Best wishes for improvement in your situation.

[ConnieD in reply to Kwinholt]

Sorry to hear that Karen, would he be willing to go to rehab or counseling ? I will keep you in my prayers!🙏🏻

[Kwinholt in reply to ConnieD]

Connie, He’s a typical alcoholic , he doesn’t think he has a problem. His day revolves around his beer. I am fortunate that he goes to work everyday and doesn’t drink there , at least for now, but that’s the first priority when he gets home. We used to be gym rats together , he a body builder and me a runner . Now I go alone . He hasn’t set foot in a gym for 3 years. I guess I just miss my husband and the person I used to be too. PD changes you everyday as well and I know I will never be the person I was before either. Thanks for listening . Karen

[ConnieD in reply to Kwinholt]

Anytime! I hope he wakes up and can be supportive again! 💕

[PDGal4 in reply to Kwinholt]

Karen, This disease is tough enough without emotional support. I feel for you. I am sure he won't agree, but have you thought of counseling? If he won't go as a couple, perhaps for you? Therapy has helped me enormously with dealing with this.

[MMmm7]

You said u stopped Sinemet one day.

It us very dangerous to stop L-dopa just like that.

A Must Read for all PWP: Once Upon A Pill by Janice Hadlock

[PDGal4 in reply to MMmm7]

Do you know where to find the book? I looked on Amazon and it is out of print and unavailable.

[MMmm7 in reply to PDGal4]

Go on google. She published it for open reading but I printed it and put ut in a binder. Quite thick.

[PDGal4 in reply to MMmm7]

Found it. Downloaded PDF. 600 pages. Plan to read on my iPad. Thanks.

[MMmm7 in reply to PDGal4]

You ate welcome!

Very interesting and informative.

I wish all PWP can read this.