Serrapeptase

[Seashore60]

Has anyone any experience with taking Serrapeptase and if so, does it help and what sort of doses do you take?

[Hidden]

Why are you wanting to use this?

[Seashore60 in reply to Hidden]

Hi Osidge,

I’ve read that it’s an enzyme that can mop up bad proteins and reduce inflammation etc. so it might reduce the build up of alpha synuclein in the brain?

[Hidden in reply to Seashore60]

It does appear to have some anti-inflammatory properties but I can find no evidence of its ability to deal with alpha synuclein

[Seashore60 in reply to Hidden]

Thanks Osidge, I guess that any anti inflammatory properties it may have could be of some benefit but it’s reducing the alpha synuclein that’s the real goal!

[partnercare in reply to Hidden]

You are right about not much evidence but I am keeping this on my short list of things to watch. Based on what I have read it is good for removing things related to waste such as scar tissue and upper respiratory congestion's. But if you have good scar tissue such as from some previous operation you may want to avoid or be careful. So, ... can it remove the bad accumulation inside the brain barrier? Have not pursued it yet as we are trying other things such as thiamine now. Would love to see more chatter on this but I agree, not much evidence.

[Seashore60 in reply to partnercare]

Yeah interesting regarding “good scar tissue etc.” I suppose like a lot of different treatments whether they’re nutritional, herbal or in this case an enzyme there isn’t a tried and tested regimen to follow so it can prove difficult to know how much to take for your particular condition.

[JAS9]

POKE! Has anyone gotten more info on this yet? Here's a review article from 2020:

ncbi.nlm.nih.gov/pmc/articl...

A paragraph discussing the use of Serratiopeptidase on rat AZ:

Another innovative and interesting application is in the treatment of Alzheimer’s disease via the reduction of amyloidosis. Serratiopeptidase was found to be as effective as nattokinase (an enzyme shown to degrade amyloid fibroid) in relieving Alzheimer’s disease pathophysiology in a rat model [64]. Oral administration of an enzyme decreased brain acetylcholinesterase activity, as well as levels of transforming growth factor ß, Fas, and interleukin-6, all of which were significantly increased in patients with Alzheimer’s disease. These results were confirmed by histological examination of brain tissue. This study demonstrates that serratiopeptidase can down-regulate the amyloidogenic pathway due to its proteolytic, anti-oxidant, and anti-amyloidogenic effects. The study was further supported by a recent report [65,66] showing the dissociation of insulin amyloids by serratiopeptidase both in vitro and in vivo. Amyloidosis is a result of misfolding of normal cellular protein to protease-resistant β-sheets making insoluble aggregates. These aggregates build up in the body and their clearance is highly difficult. The amyloid dissociation ability of serratiopeptidase was better than that of the standard amyloid dissociating agent, nattokinase. This novel approach paves the way to explore the therapeutic potential of serratiopeptidase in different amyloid-related disorders

[Nigmoss in reply to JAS9]

Hi

I am new on here and was diagnosed with Parkinson's just over a year ago, yesterday someone sent me the following link regarding the use of Serrapeptase, how credible it is I have no idea but thought it worth the mention.

Actually just noticed he has noted it as Serropeptase on the presentation so that doesn't bode well for starters.

youtube.com/watch?v=PpKsGcb...(Not working as expected?)

[JAS9 in reply to Nigmoss]

This doctor should have mentioned that this treatment is a guess. I just got a bottle of it, and I know that others have started on it, so we will see what happens. Just one thing thing . The mg or IU "amount" for all enzymes do not matter at all and can vary. It is only the enzyme strength or enzyme activity units that matters and each enzyme is measured differently. The standard for Serrapeptase is just called SU or SPU. There's no translation for the mg amount because each company's extraction/purification method and medium are different. So when he talks about dosing I don't think he is very helpful.

[PDWarrior1900]

I have PD for more than a year (no DX yet). I've been taking about 550,000 units total (2 tablets) daily for several months.

Serrapeptase was featured on Youtube videos from Dr Mandel and Dr Berg.

I'm taking over 30 other supplements, plus sun, sauna, exercise, etc.

My PD is still ... very slowly... progressing.