The vitamin that may stop brain cell death in Parkinsons disease

[marcet]

Very interesting article, certainly worth a try.....

care2.com/greenliving/the-v...

[jeffreyn]

The article states: "a readily-available and affordable vitamin"

The article is about recent research involving nicotinamide riboside, which in my understanding is actually pretty expensive.

The SoPD blog has a recent post about this (and related) research:

scienceofparkinsons.com/201...

[jeffreyn in reply to jeffreyn]

Recent HU discussion of this SoPD blog post:

healthunlocked.com/parkinso....

[LAJ12345]

It is very expensive. The ones you can buy are around $40 per month for a 250mg per day dose so 2-17 g per day would cost a fortune to maintain!

[Farooqji in reply to LAJ12345]

They have corrected the recommended dose. The updated version says "A typical dose is between 2 and 17 milligrams daily, although more may be needed for those already experiencing Parkinson’s disease. Check with your doctor before using."

[LAJ12345 in reply to Farooqji]

Interesting. Thanks. The tablets come in 125mg in the brand I have. I wonder how to get the dilution and how stable it is. Maybe mix an opened capsule with powdered stevia to water down and add to food? Any ideas?

[LAJ12345 in reply to Farooqji]

Where is the updated version please?

[Farooqji in reply to LAJ12345]

care2.com/greenliving/the-v...

Update 7/9: An earlier version of this article stated an incorrect typical dose of nicotinamide riboside. It should be 2 to 17 milligrams.

[M1tz1]

Thank you for this, Marcet.

[MWLE]

Is about $1 for 250 mg of NAD today. It would be at least $8 per day for the 2 g. That is still cheaper than most PD meds. However, this was much cheaper about a year or two ago! The supplement industry is responding to the increase demand and raising prices 2+ folds.

[marcet in reply to MWLE]

What brand do you use ?

[MWLE in reply to marcet]

I started my parents on TRU Niagen, but I am using Life Extension.

[bassofspades]

I found a trial size bottle of this on Amazon. 2 week supply called the Believer Bottle. Cute, huh?

HPN Nutraceuticals NIAGEN - BELIEVER BOTTLE - FREE 2 DAY SHIP - The Original Patented NAD+ Booster w Nicotinamide Riboside (Nr) - 28 Capsules amazon.com/dp/B01DZ3AQHU/re...

Wondering how many feet of dendrites i can grow in 2 weeks,!?

[KemptonD]

clinicaltrials.gov/ct2/show...

Link for statement for trial:

Experimental: Nicotinamide Riboside

nicotinamide riboside, 1000mg daily for the duration of the trial (52 weeks). Dosage form is tablets.

[bassofspades]

I finished my 2 week "believer bottle " yeah, nah, im not a Believer!

[jimcaster in reply to bassofspades]

I'm not necessarily a believer, BUT I think the cost is minimal and the potential upside is huge, even if cell preservation does not produce quick or obvious results. I'm sticking with 2 grams of thiamine and 500 mg of nicotinamide riboside unless I'm convinced they don't help. I think thiamine has more immediate benefits, but nicotinamide riboside (B3) may be equally good in the long run. Tru Niagen (B3) sits on the shelf and gets used right along with Solgar Thiamine hcl (B1) for me.

[bassofspades in reply to jimcaster]

Long term is probably the way to go, but for me, i already take too many supplements. True niagen is actually one of the more expensive ones. Good luck my friend!!!

[jimcaster in reply to bassofspades]

Thanks, Bass! BACK ATCHA! My hope is to tread water long enough for someone to come up with a cure or at least a stop of the progression. Maybe we've already accomplished that with B1. I sure hope so!

[KERRINGTON in reply to jimcaster]

Hi, are you still using Tru Niagen ? If so, any luck ? Happy New Year !

[jimcaster in reply to KERRINGTON]

Yes! I think TruNiagen is a long term benefit. I don't think I'll ever know in the short term if it helps, BUT the long term mitochondrial benefit seems hard to refute. I will take it forever and would even if I didn't have Parkinson's disease. I even have my wife taking it. Joe (Sunvox) has written about it extensively and persuasively.

[KERRINGTON in reply to jimcaster]

Thanks for the info !