AAV2-GDNF for Advanced Parkinson s Disease

[Farooqji]

Just found this trial while searching for GDNF based studies. The gene transferred in this study, called AAV2-GDNF, may help produce GDNF to protect the damaged brain cells.

clinicaltrials.gov/ct2/show...

Does anyone know about the latest status

[danfitz]

Nice find my friend. Wow. A 15 year time frame from start to finish. I wonder how it’s going.

[JohnPepper]

GDNF will not cure Pd. However, GDNF does repair the damaged brain cells, which means it helps our brain to produce more dopamine and that makes us feel better.

The problem is that we cannot take GDNF orally because it will not get through the blood brain barrier (BBB). But nobody appears to want to find a way to get the body to produce more GDNF in order to reverse the symptoms of Pd.

I have managed to reverse my symptoms and have continued to keep them in the reversed state for the past 15 years. What I do to achieve this ideal state is fast walking. That may not be an option for all patients but maybe there are other ways of getting the brain to produce more GDNF.

What if we, the patients with Pd, were to raise enough money to pay for a controlled scientific study to find out what will produce the MOST GDNF.

Instead of spending a fortune on another drug that will only deal with our symptoms and not give us the next best thing to a cure, which is more GDNF, we should put our money where it will help us to get better!

LET US STAND TOGETHER AND FIND A NATURAL WAY TO PRODUCE MORE GDNF IN OUR BRAIN! SET UP A FUND TO MAKE THIS HAPPEN!

Come on everybody, wake up and see what is happening to us!

[fossygma in reply to JohnPepper]

I'm with you john, count me in.. Anything else other fast walking (how long) ?

[JohnPepper]

It is too much to put into the blog. contact me on reverseparkinsons.net and I will send you lots of food for thought.