C/L 10/100

[jombi]

Does anyone know why my neuro would prescribe C/L 10/100? Doesn't that mean there is less cardidopa to guard against nausea? Thanks

[MBAnderson]

Yes, that is what it means. As you know, 25/100 is what is normally prescribed.

[Enidah]

I didn't know they even made it in that dose. It would be interesting to see what your doctor says about why you were prescribed that.

[park_bear]

If you are taking many of these per day the lower dosage per pill of carbidopa is appropriate. If you are not taking many, there is only an issue if you're feeling nausea. Some researchers claim carbidopa causes adverse effects. I do not know that this is true, but as long as this medication agrees with you there is nothing wrong with it. If you do feel nausea, then ask for the 25/100 version.

[jombi in reply to park_bear]

Thanks park bear. That makes sense to me. Haven't taken any yet.

[Juliegrace]

I just switched from 25/100 after two years to 10/100 two days ago. I take a very low dose, 300-350 mg daily. I have less dyskinesia with the 10/100, which is why my doc prescribed it.

[jombi]

Thanks-that explains alot. Maybe my neuro knows more than I was giving him credit for

[parkie13]

ncbi.nlm.nih.gov/pmc/articl...

This article might explain the reason for prescribing 10 / 100 mg. It explores side effects from Carbidopa. even if one doesn't follow Marty hinz protocol you just can't ignore the statistics of mortality and Parkinson's. Take a look at the boxes also, the graphs and the side effects of Carbidopa. Depending on the dosage the depletion of B6 vitamin and its consequences takes about 5 years as a minimum.

[MBAnderson in reply to parkie13]

Seems to me, this is a bombshell study. Important find parkie13.

The death rate from Parkinson’s was in decline until carbidopa was introduced, at which point the death rate began increasing. If L-dopa does not accelerate progression and/or lend itself to tachyphylaxis, which seems to be the consensus, that would be a moot point if carbidopa kills you.

[parkie13 in reply to MBAnderson]

I tried a do-it-yourself Marty Hines protocol. The l-tyrosine raised my blood pressure very high. I feel that I am between a rock and a hard place, I don't know what to do. As I said I am on CR sinemet a couple months now.

[park_bear in reply to parkie13]

I have been in denial of this information thinking it was just a Marty Hinz thing. It seems that is not so - there seems to be agreement that carbidopa/benzaseride are bad actors. See here for example: ncbi.nlm.nih.gov/pmc/articl...

As it happens I take only one Sinemet CR 50/200 in the evening. 12 hours later it is washed out of my system. At this point I take a vitamin B multi which includes B6. So my body has half of the 24 hour period to recover.

[Hidden in reply to park_bear]

Multi has 5mg B6. Should be 100mg//day

[jombi]

Thanks for article- very interesting and - concerning

[MBAnderson]

park_bear sites an equally important study. They both, essentially, make the same point. I began listing the most salient quotes, but found there are so many of them, I'd be pasting the whole study, so instead I'll leave it at this.

"Responsible physicians create an environment where optimal symptom control nurtures healing. Two medications with no efficacy claims have been prescribed for the iatrogenic mismanagement of a nutrient, L-dopa, turning it into a drug which depletes other systems.3,12,13,69 Their only indication is to alleviate nausea, a benign condition, while having the ability to profoundly compromise hundreds of system functions.3,69 In our opinion, use of these medications is a violation of the physician’s oath to first, do no harm. These drugs can create fatal events, clinical deterioration, drug-induced sequelae, and risks where none previously existed due to profound multisystem nutritional collapse.12,13,18,19,70–74,78–83 Nausea induced by improper administration of the nutrient L-dopa should not be addressed with drugs whose mechanism of action is system-wide vitamin B6 RND, which is especially true when a drug-free nutrient management approach is available."

If anyone knows of studies that refute these, please site them, otherwise, they reinforce my own decision to take as little Sinemet as possible -- which makes Mucuna Pruriens (and other natural sources of L-dopa) all the more viable.

I urge everyone to read these carefully.

Boo-hoo.

[jombi]

Mucuna looking better all the time