My mum takes 150mg of azathiopine daily and her liver tests come back ok. The problem is she always seems so tired and her joints seem to really hurt her to the point that the swell and she can't move. Sometimes her hands go into like a claw or she cant move with the pain and she seems to feel very sick alot. Before these pains start she gets really cold and shaky and has agabouts. Her foot at the moment is swollen and she can't move it. does anyone else suffer with these or what else can be part of the illness?