Scientists are beginning to unravel one of the biggest challenges with immunotherapy: why some people with cancer respond to the treatment, while others may not respond at all.
In a new study, researchers at the UCLA Jonsson Comprehensive Cancer Center found patients with a particular type of human leukocyte antigen (HLA), a protein scaffold involved in presenting pieces of proteins described as peptides to the immune system, were particularly likely to benefit from immunotherapy. This research explained a surprising finding seen among patients in the clinic.
The data, published in Nature Cancer, focused on a type of HLA called B44, which is present in approximately half of people. In melanoma, patients with HLA-B44 tend to do well with immunotherapy, but in non-small cell lung cancer, the most common type of lung cancer, most people with HLA-B44 did not do as well as people without HLA-B44. In the study, authors figured out that the different responses were driven by the different types of mutations that are common in each of the cancer subtypes.
I'm really tired with all these ideas about lung cancer
Why don't people want to quit smoking?
Has anyone had a Spirometry test recently?
Looking for guidance 
