Itchy skin in bed after months on entresto

[Bigmark61]

I’ve been on entresto middle dose for a year and have had Itchy skin on and off when I go to bed, but recently has been getting worse, I’ve also a runny nose for a good few months and developed Reynard's worse in the cold weather and painful Hands and feeling really shattered when I waken up in the morning Has anyone else developed these sort of issues later on when using entresto I also take Bisoprolol 3.75mg and tramadol for back pain Should I ring my GP or cardiac nurse?