Very high Lipoprotein (a)

[pickety]

In December my heart consultant told me he was concerned I had raised Lp(a), over 800mg/L, way above the 300mg/L threshold. Anything above 500mg/L is a considerable risk factor. He raised my statin yet although my cholesterol has reduced, the Lp(a) has increased to 1104. Naturally I am very worried. Any advice or similar experience welcomed.

[MichaelJH Heart Star]

Hello and welcome to the forum! Sorry I cannot help on this. I asked for this test after having read about it but was refused as it is "researchy". Not long after I developed angina culminating in a quadruple bypass last year. I will watch your thread with interest.

[fergusthegreat]

Hi Pickety, from my own experience, lipoprotein a I believe is unresponsive to statins and dietary changes. The only drug that works I think is naicin however this comes with a lot of side effects.

[Hidden]

Useful post.

I'm considering to ask for this test, too.

Were you offered the test in one of the major London hospitals, may I politely ask?

Does statin lower LP (a)?

Has anyone had ApoB/ apolipoprotein B100 test?

Apparently, one UK Doctor queries as to why UK isn't using it.

Canada (a similar HC system) incorporated this test in their Guidelines

as it's proven the test is far more reliable AND many pensioners/elderly patients would be spared from being on statin unnecessarily and suffering from statin side effects in their remaining years.

[Jack2019]

I live in Canada, the test a GP will run is ApoB100. If your triglycerides , Hdl and A1c are within range they will not do an LPa, as you're likely to have healthier cholesterol proteins. My understanding on statins is that they increase receptors on the liver that take up the extra cholesterol out of the blood, thus lowering your ldl numbers, the problem with that is that the receptors pick up the healthy large particle(pattern A) ldl , leaving the remaining small oxidized (pattern B) ldl particles in your blood stream which i think is LPa. This is my laymans understanding only. I would be interested what others on this forum know about these tests. Thanks

[Jack2019]

Thanks for that response. I asked my cardiologist for a coronary calcium scan, he said it wouldn't be accurate as apparently the stents give off a reflection? preventing a clear view. Too bad, I was really hoping to get one. I get your point about the trig/hdl ratio and if its close then no need to worry about LDL. Like yourself I do a low(ish) carb. diet and I eat in an 8 hour window as I believe it is the best approach to keep down triglycerides and up your HDL. I didn't know about Vitamin C, I will look at the Professors you tube channel. Thanks again.