So I came across this study years ago and forgot about it. Long before I got to where I am today in terms of a complex regimen I was already exercising regularly because I had read this report. Today I happened across this information once again so I thought I would share the info. Putting this together with the work done in Parkinson's and I find it, personally, convincing evidence of the power of simple exercise to alter the progression of neurodegenerative diseases:
Exercise and Genetic Rescue of SCA1 via the Transcriptional Repressor Capicua
science.sciencemag.org/cont...
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Effect of High-Intensity Treadmill Exercise on Motor Symptoms in Patients With De Novo Parkinson Disease
jamanetwork.com/journals/ja...
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Running wheel exercise reduces α-synuclein aggregation and improves motor and cognitive function in a transgenic mouse model of Parkinson's disease
journals.plos.org/plosone/a...
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Influence of anaerobic and aerobic exercise on age-related pathways in skeletal muscle
sciencedirect.com/science/a...
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My progression is stopped for now. Here's my regimen.