In a new paper, scientists from La Jolla Institute for Immunology (LJI) bring together research findings from COVID-19 researchers around the world. The results are striking: human T cells can target more than 1,400 sites on the SARS-CoV-2 virus.
“Our lab and many others have shown this very broad and diverse T cell response,” says LJI Research Assistant Professor Daniela Weiskopf, Ph.D., co-author of the Cell Host & Microbe review.
This kind of research review, called a “meta-analysis,” pools the results of multiple studies, and the researchers give close consideration to how the studies were conducted.
In the case of COVID-19, a global meta-analysis of T cell response studies is especially helpful because different patient populations can have vastly different immune responses, based on their genetic differences and past disease history.
“This really highlights how the study of SARS-CoV-2 has been a global undertaking,” says LJI Professor Alessandro Sette, Dr.Biol.Sci, senior author of the review and member of the LJI Center for Infectious Disease and Vaccine Research. “To combine information from all the different labs is a powerful thing.”
bioengineer.org/a-covid-fig...
Cell Host & Microbe. Research Paper:
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