Bisoprolol dosage.: Hi all, looking for... - Atrial Fibrillati...

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Bisoprolol dosage.

FedupwithAF profile image
45 Replies

Hi all, looking for others experience with Bisoprolol.I've been talking this medication for sometime, the GP prescribed 5mg twice a day, usually taken in the morning and evening.

However reading the medication leaflet is suggests any dosage should be taken once a day, therefore 10mg once a day.

So my question is, how do others take it?

Thanks for your assistance.

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FedupwithAF
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45 Replies
10gingercats profile image
10gingercats

my cardiologist has fiddled with my Bisoprolol a couple of times and it has always been twice daily but with different doses depending upon my heart rate when she checks me. The most recent time was in the summer and I took an increased dose in the morning 3.75 on cardios advice instead of 2.5 in the morning and 2.5 in the evening. This messed up my day with the higher morning dose and i reduced it back to 2.5 and 2.5 when i began to feel ill on the larger morning dose with the smaller eve. dose. I can see I am going to have a battle to get it back to what suits me .I suggest you be guided by how you feel. If the 10 you take now seems to work for you stick with it and 'fiddle not!'

FedupwithAF profile image
FedupwithAF in reply to10gingercats

Hi 10 gingercats, thanks for your response, looks like you have a more informative medical practitioner than I, in my experience, if you're still experiencing AF, 'keep increasing the dose'.

jeanjeannie50 profile image
jeanjeannie50

My AF nurse told me that Bisoprolol stays in the body for 24hrs so it's generally taken once a day. However, sometimes the dose can be split like yours is as 10mg is a hefty dose to take all at once. Do you know what your heart rate is on that dose?

Jean

FedupwithAF profile image
FedupwithAF in reply tojeanjeannie50

Hi Jean, thanks for your response HR normal 65 bpm.

jeanjeannie50 profile image
jeanjeannie50 in reply toFedupwithAF

That sounds a good rate. How are you feeling?

Parya profile image
Parya

Hello I take bisoprolol 10mg once a day in the morning I have only been diagnosed for 3 months also on digoxin for heart failure and furosemide can't get my heart rate below 93 at the moment so quite envious of yours!

FedupwithAF profile image
FedupwithAF in reply toParya

Thanks for your reply Parya.

BenHall1 profile image
BenHall1

Hiya,

When I was first diagnosed with AF in Jan 2010, the consultant who attended put me on Bisoprolol 5 mg to be taken in the morning. After a few months this managed to generate random, full flow nose bleeds. My GP then changed it to be taken at night ... no more nose bleed, no more problems. Stayed in this dose until 2022/23 when my GP decided that Nebivolol 5mg would be better and again to be taken at night. Finally, in April 2024 when my heart kicked off again I consulted a Cardiac Consultant of my own choosing and he switched me to Sotalol , 40mg in the morning and 40 mg at night.

FedupwithAF profile image
FedupwithAF in reply toBenHall1

Hi Ben, thanks for your reply.

Ppiman profile image
Ppiman

One of the advantages of bisoprolol is its long half life, which makes it perfect for once daily dosing. It also soon reaches a “steady state” in the bloodstream meaning twice daily dosing shouldn’t have any point. But… it seems some do like twice daily.

10mg is a high dose and that might be why your GP split the dose. Individuals do seem to have different responses to the same dose of the drug.

Steve

FedupwithAF profile image
FedupwithAF in reply toPpiman

Hi Steve, thanks for your comments.

FedupwithAF profile image
FedupwithAF in reply toPpiman

Hi Ppiman, thanks for your comments, interesting!

Vonnegut profile image
Vonnegut

How different we all are! The lowest dose of 1.25 mg was too much for me to take daily! It brought my heart rate down too low and does nothing for the irregularity that is part of our problem. Good luck

FedupwithAF profile image
FedupwithAF in reply toVonnegut

Hi Vonnegut, thanks for your comments.

bobby1290 profile image
bobby1290

Admit I had been on 2.5mg twice daily, and struggled, with my BP going low if I was sitting for a while, for if I got up too quick, my legs would go wobbly and overall a little light headed. 2 separate occasions I lost consciousness when jumping out of bed too quick. So dropped dose in half, and feel back to normal....although carry tablets with me, just incase I need to take an extra one.

FedupwithAF profile image
FedupwithAF in reply tobobby1290

Hi bobby, thanks for your reply, seems medication for AF has different effects on different people.

Tellingfibs profile image
Tellingfibs

My cardiologist told me to split the dose once he had increased it to 10 mgs, but I had already been taking it twice daily even on a lower dose. He said that was fine. I feel it spreads it out a bit rather than taking a whopping dose all at once. Bisoprolol is given for slowing the HR and for lowering blood pressure, so maybe it depends on the reason for taking it.

Annie

FedupwithAF profile image
FedupwithAF in reply toTellingfibs

Hi Annie, thanks for your comments.

Sleepyzz profile image
Sleepyzz

I take mine split between morning and evening was told to by cardiologist I take 5mg morning and 2.5 mg evening was originally 5and 5 but now I only take extra 2.5 if in afib as agreed with cardiologist

FedupwithAF profile image
FedupwithAF in reply toSleepyzz

Hi Sleepy, thanks for your comments.

Tomred profile image
Tomred

I take 1.25mg daily and add another 1.25 when i go into afib, first prescription was 5mg once daily and i couldnt get out of my chair.

FedupwithAF profile image
FedupwithAF in reply toTomred

Hi Tom, thanks for your comments.

Belle11 profile image
Belle11

I've always been advised to take it once a day, and I take it in the evening with dinner, as it tends to make me a bit short of breath on exercise. My dose was 10mg for several years until I persuaded a new cardiologist to slowly reduce it, which helped somewhat the shortness of breath (though still not perfect). I'm on 5mg now once a day. HR usually in the 50s.

If your dosage suits you, I imagine there'd be no need to change what you're doing.

FedupwithAF profile image
FedupwithAF in reply toBelle11

Hi Belle, thanks for your comments.

Fannyphasbees profile image
Fannyphasbees

I started on 5 , then was increased to 7.5 and now take 10mg daily. I was told to take it at 8am . Warfarin at 5pm. I hope that helps.

FedupwithAF profile image
FedupwithAF in reply toFannyphasbees

Hi Fannyphasbees, interesting, thank you for your comments.

jd2004 profile image
jd2004

When I was on Bisoprolol I was told to take 1 x 10 mg a day in the morning as it could make HR too slow at night. Maybe that’s why you’ve been advised 2 x 5.

FedupwithAF profile image
FedupwithAF in reply tojd2004

Thanks for your reply Jd, interesting comments.

RickyM profile image
RickyM

I am in permanent AF. My bisoprol dose is 1.25 taken first thing is enough to give me a resting heart rate 60-80. Exercising is where my HR goes out of control.

FedupwithAF profile image
FedupwithAF in reply toRickyM

Hi Ricky, thanks for your reply, sorry to hear about the permanent AF, is there nothing that can be done to revert to normal rhythm?

RickyM profile image
RickyM in reply toFedupwithAF

Hi there,I've had it for 11 years now.

I had 3 cardioversions back then with no luck.

Decided against anything else, at that time, as my symptoms were minimal.

It sounds to me like some people must be on a too higher dose of bisoprol for just HR control. I accept there may be other reasons.

Best of luck with your dosage quest.

mbheart profile image
mbheart

10 mg each night since 2018

FedupwithAF profile image
FedupwithAF in reply tombheart

Hi mbheart, thanks for your reply.

hausjac profile image
hausjac

I've taken mine, now 7.5mg but was 10mg for many years last thing at night so the side effects aren't too bad

FedupwithAF profile image
FedupwithAF in reply tohausjac

Hi hausjac, thanks for your reply.

Tommyann profile image
Tommyann

x2 a day

FedupwithAF profile image
FedupwithAF in reply toTommyann

Thanks Tom.

opal11uk profile image
opal11uk

10mg mornings

FedupwithAF profile image
FedupwithAF in reply toopal11uk

Hi opal, thanks for your comments.

magendomike profile image
magendomike

I have been taking 5 mg twice a day for years seems to suit me as bp and pulse 60 - 70 are fine tho a little lower late evening when in my chair after supper. I still xercise on treadmill 2 x 20 mins p week not breathless tho not going v fast. When xercising in af pulse for anyone is all over the place but below 125 ish for me. Feel fine on it. Am 81. Mike

FedupwithAF profile image
FedupwithAF in reply tomagendomike

Hi Mark, thank you for your comments.

TracyAdmin profile image
TracyAdminPartner

Thank you for your post, I can read you have already received advice from fellow members of the Forum. All medications are prescribed based upon personal details such as age, weight, other medications and underlying health conditions and so vary on an individual basis and should ideally be discussed with your doctor. For a brief overview of Bisoprolol and other antiarrhythmic medication, download:

Atrial Fibrillation and Drug Information booklet:

UK and International: api.heartrhythmalliance.org...

US: api.heartrhythmalliance.org...

Kind regards

TracyAdmin

booklet
FedupwithAF profile image
FedupwithAF in reply toTracyAdmin

Hi Tracy, thank you for the information.

LadyLawson profile image
LadyLawson

I take 2.5mg morning and evening. My cardiologist is happy for me to take it twice a day. But he also says that 5mg once a day would be fine. So there seems to be some flexibility to have it once or twice daily.

FedupwithAF profile image
FedupwithAF in reply toLadyLawson

Hi Lady, thank you for your comments.

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