apixiban and reduction in stroke risk - Atrial Fibrillati...

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apixiban and reduction in stroke risk

Robfromwales profile image
10 Replies

I am sure this has been covered in previous posts but can someone remind me of the answer to the question … if we are on apixiban due to our AF how much general cover does it give us against non AF related TIAs or strokes? I appreciate every person is different and their risks will vary but any one know the general picture.

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Robfromwales profile image
Robfromwales
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BobD profile image
BobDVolunteer

The general stroke prevention figure for anticoagulants of 70% is for all strokes. AF makes us five times more likely to have a thrombotic stroke of any kind. As we know AF related strokes account for approx 20% of all strokes but 80% of the least recoverable ones hence the emphasis on anticoagulation for AF patients

Robfromwales profile image
Robfromwales in reply toBobD

thanks Bob . I had hoped you would reply as I know you are a fount of knowledge on such matters. So the general stroke risk is reduced by 70 per cent with ACs? Btw / during recent OHS for Ascending aortic graft - I had my left atrial appendage closed which I understand helps reduce clots from AF

BobD profile image
BobDVolunteer in reply toRobfromwales

So I believe.

waveylines profile image
waveylines in reply toRobfromwales

Are you still required to take an anti coagulant despite having the left atrial appendage closed? My understanding is that once this is done anti coag is no longer required..... Well that is what my EP and surgeon have told me - am awaiting a heart op that also includes this.

Robfromwales profile image
Robfromwales in reply towaveylines

The advice from my surgeon was that this reduces risk of AF related stroke by 60 per cent. As others have commented over time on here, you can’t undo a stroke so I am not advocating coming off them for myself.

waveylines profile image
waveylines in reply toRobfromwales

Interesting Robfromwales.... My surgeon says closing the flap reduces the risk of stroke by 80% so no need for anti coag. My EP said the same thing. Infact they do it when anticoagulants can't be tolerated. . I think there are differing views....

Robfromwales profile image
Robfromwales in reply towaveylines

Yes indeed. As at the moment there are no issues with apixiban I intend to stay on it and that’s why I asked about the efficacy of broader stroke non AF cover

secondtry profile image
secondtry

If I was you I would continue on ACs for a couple of years more due to increased protection from strokes caused by other non-AF issues unless you have concerns you might be an internal bleed risk eg stomach or exposure to a head injury.

Robfromwales profile image
Robfromwales in reply tosecondtry

I am on for life as far as I am concerned!

JOY2THEWORLD49 profile image
JOY2THEWORLD49

Hi

I had a stroke before AF was diagnosed.

I was not on any meds except for B12 Solgar 1000ug 2-3 days 1 nugget sublingual.

But 4 days in hospital I was diagnosed with possible Papillary Thyroid Cancer. The biopsy showed to be correct a1.9mm carcinoma in right lobe, tiny bit in left and 2 out of 12 removed lymphs on right affected.

I did have symptoms of sweating profusely, unable to keep my temperature regulated, rest at completed stairs or elevation.

No lumps on neck, all thyroid levels normal.

I'm not sure whether like me with no feeling that your heart is in trouble would one know.

cheri JOY. 74. (NZ)

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