Adizem/Flecainide Side Effects

[PAP48]

I take 50 mg Flecainide am and pm and am taking Adizem 120 slow release in the evening. Does anyone else have a problem with increased need to visit the loo in the evening or night time? From about 6 pm in the evening I'm frequently going to the toilet, I go before I go to bed, then by midnight(ish) I feel the need again and once or twice more during the night. During the rest of the day I don't have the problem! Input from anyone would be greatly appreciated.

[mjames1]

Could have other causes, but nocturia (frequent night time urination) is associated with calcium channel blockers like Adizem.

I just recently stopped Adizem and have noticed that the frequency of my nighttime urination has decreased. That said, I still prefer Adizem over beta blockers, which have their own set of side effects.

Jim

[PAP48 in reply to mjames1]

Thanks Jim. All seems to tie up. May I ask what time of day you took Adizem? I’m thinking maybe it’s better to take it in the morning? I have to say that my PAF has been much better since taking this combo! Are you well enough not to have to take it any more? Penny

[mjames1 in reply to PAP48]

I always took the fast acting tabs. Either twice a day -- 8am and 8 pm or sometimes 4x/day 8am, 4pm, 8pm, 4am

Just had an ablation, so protocol was to stop Adizem and Flec after a month. Hopefully, I won't need them again, but they kept me out of afib for a year.

Jim

[PAP48 in reply to mjames1]

I hope, too, you don't need any meds again. I'm pretty sure now my trips to the loo are, indeed, linked to Adizem. Hey ho, if it's not one thing! Keep well. Penny

[ElizabethBee]

Hi. I have just joined this site and so glad I did. It has helped me enormously after just having a diagnosis of AF and feeling like it was the end of the world. Having just read your post (I’m glad I did) I’ve realised that my nocturnal visits to the loo are down to my Adizem. I wondered why I’m visiting the loo 2 to 3 times during the night. I take my Adizem first thing in the morning so I don’t think that changing your habit of taking them at night will alter the fact that you still need to visit the loo throughout the night.

[Buffafly in reply to ElizabethBee]

Night loo visits can also be a side effect of AF especially if you have a low degree of heart failure. It’s worth mentioning to your GP. If your ankles swell (also unfortunately a side effect of diltiazem) it is a good idea to ask for support stockings if you can bear them ❤️‍🩹

[ElizabethBee in reply to Buffafly]

Buffafly, thank you. I don’t have swollen ankles but obviously as you point out, my nightly visits to the loo could be a side effect of heart failure and not my Adizem. I just thought it a coincidence that PAP48 experienced nightly visits to the loo and is taking Adizem medication too. I’ll speak to my consultant when I see him next. Thanks again. ❤️

[PAP48 in reply to ElizabethBee]

I think you're right ElizabethBee. I'll keep taking Adizem at night as recommended. The loo trips are a small price to pay, I think, for keep the Afib at bay, at least for the time being. Keep well and thank you for replying. x

[secondtry]

No experience with Adizem but been on 200mgs Flecainide for years.

I also have had nocturia for years, usually twice a night, sometimes 4 or 5, the latter I think due to what I have for my last meal at 5pm; meat seems to generate more nocturia in my case. Still testing different meal choices. It's also possible it could be caused by anxiety from poor breathing whilst asleep due to a frequently part blocked left sinus/nostril or dreams. I say this because during the day anxiety has that effect. In reality it may be a mix of reasons.

[PAP48 in reply to secondtry]

Thank you for replying secondtry. Interesting you say about anxiety from poor breathing, I also have bronchiectasis and asthma so sometimes my breathing is worse than others. Last night, actually, was a good night for me, only one extra trip! Keep well.

[bassets]

I am taking virtually the same and try not to drink much in the evening, making up for it next morning. But I was dashing to the loo 2 and three times a night until I was prescribed an oestrogen replacement and the problem is much easier - would that help?

[PAP48 in reply to bassets]

Hi Bassets - did your GP prescribe the oestrogen replacement and was it specifically to treat this particular problem? I have an appointment with my GP on Monday, I'll discuss it with her. Keep well.

[bassets in reply to PAP48]

It was sometime ago and yes she did prescribe oestrogen pessaries for that problem. Oddly enough I have started on it again and sleep like a log .

[lizzieloo2]

HI. I take 300mg Diltiazem daily at 11.00am and 100mg Flecainide as a pill in the pocket. I am due to have an ablation next month after 10 years of paroxysmal AF which is becoming more frequent. I have to get up for the loo at least twice during the night normally but when I have an episode of AF, I need to pee every half hour, sometimes up to 6 or 7 times in the hour or two it takes before the Flecainide kicks in and puts me back into sinus rhythm.

[PAP48 in reply to lizzieloo2]

Thank you for replying lizzieloo2 - I know exactly what you mean about the toilet problem when in AF! Every half hour until I get back into sinus rhythm. Good luck with your ablation and hope it sorts you AF out. Take care.

[Overeating in reply to lizzieloo2]

Biopsal , now I know why I have to go to the loo more,I take what should be 5 which I have only taken one untill my perscriction gets put right,I am still suffer i from 5 5 made me get tired when I walk as I have to keep stopping and not be able to walk more than half a mile for seven months except one week I took old bp so I enjoyed myself.I find it more things to do when I stay at home. When I had an aneasetic I had af and I feel I could get dizzy and I have to have another procedure with my arm inOctober a bit worrying..

[Karendeena]

I am just the same, I don't go much in the day then up at least 3 times in the night, still can't find the answer so I will see with interest what others say