Pulsed Field Ablation is one of the latest, if not the latest, advancement in ablation technique. Previously limited to the pulmonary veins, there now has been a development to address also the left atrial posterior wall:
onlinejacc.org/content/76/9...
We are living in enlightening times to manage our condition as new breakthroughs are on the horizon.
Hi Cuore 😊 I have posted about PFA and similar technology a number of times on here and I have been following the trials with interest.
More information here...
dicardiology.com/content/pu...
''𝘙𝘦𝘴𝘶𝘭𝘵𝘴 𝘴𝘩𝘰𝘸 𝘢𝘤𝘶𝘵𝘦 𝘦𝘭𝘦𝘤𝘵𝘳𝘪𝘤𝘢𝘭 𝘪𝘴𝘰𝘭𝘢𝘵𝘪𝘰𝘯 𝘸𝘢𝘴 𝘢𝘤𝘩𝘪𝘦𝘷𝘦𝘥 𝘪𝘯 100 𝘱𝘦𝘳𝘤𝘦𝘯𝘵 𝘰𝘧 𝘱𝘢𝘵𝘪𝘦𝘯𝘵𝘴 𝘵𝘰-𝘥𝘢𝘵𝘦 𝘢𝘯𝘥 𝘵𝘩𝘦𝘳𝘦 𝘸𝘦𝘳𝘦 𝘯𝘰 𝘵𝘢𝘮𝘱𝘰𝘯𝘢𝘥𝘦𝘴, 𝘴𝘵𝘳𝘰𝘬𝘦𝘴 𝘰𝘳 𝘱𝘩𝘳𝘦𝘯𝘪𝘤 𝘯𝘦𝘳𝘷𝘦 𝘪𝘯𝘫𝘶𝘳𝘪𝘦𝘴. 𝘜𝘱𝘰𝘯 𝘤𝘰𝘯𝘤𝘭𝘶𝘴𝘪𝘰𝘯, 𝘵𝘩𝘦 𝘴𝘵𝘶𝘥𝘺 𝘸𝘪𝘭𝘭 𝘳𝘦𝘱𝘰𝘳𝘵 𝘵𝘩𝘦 𝘳𝘢𝘵𝘦 𝘰𝘧 𝘢𝘳𝘳𝘩𝘺𝘵𝘩𝘮𝘪𝘢-𝘧𝘳𝘦𝘦 𝘴𝘶𝘳𝘷𝘪𝘷𝘢𝘭 𝘢𝘵 12 𝘮𝘰𝘯𝘵𝘩𝘴, 𝘢𝘯𝘥 𝘱𝘳𝘦-𝘴𝘱𝘦𝘤𝘪𝘧𝘪𝘦𝘥 𝘴𝘦𝘤𝘰𝘯𝘥𝘢𝘳𝘺 𝘢𝘯𝘥 𝘢𝘯𝘤𝘪𝘭𝘭𝘢𝘳𝘺 𝘦𝘯𝘥𝘱𝘰𝘪𝘯𝘵𝘴, 𝘪𝘯𝘤𝘭𝘶𝘥𝘪𝘯𝘨: 𝘱𝘳𝘰𝘤𝘦𝘥𝘶𝘳𝘢𝘭 𝘰𝘶𝘵𝘤𝘰𝘮𝘦𝘴, 𝘲𝘶𝘢𝘭𝘪𝘵𝘺 𝘰𝘧 𝘭𝘪𝘧𝘦 𝘢𝘯𝘥 𝘢𝘳𝘳𝘩𝘺𝘵𝘩𝘮𝘪𝘤 𝘴𝘺𝘮𝘱𝘵𝘰𝘮𝘴.
The Mayo clinic is involved in one trial with Atrian .
siliconrepublic.com/start-u...
I think this looks very promising..
Hi Doodle68. I was off the computer for almost two months so sorry I missed your posts. So glad you kept this forum up to date on recent breakthroughs. We need that to offset the doom and gloom some members may feel.
Also, thank you for the three links. I am looking forward to digesting the information.
Just a couple of observations - this appears to be selective trial if I am understanding the terminology that all who took part had been pre-selected to be treated? Second Observation - 80% were male??? I know it is unethical to do blind trials of this nature but couldn’t see much about criteria for selection - but I did only skim it.
As you say - any advance is welcome if it really does improve outcomes.
Absolutely, CDreamer. There was a lot of selectivity in this trial because at its current stage, it is not suitable for everyone. But, the very fact that medicine is exploring out of the box procedures compared to the current ones gives hope that eventually procedures for AF will be routine, short, and permanent. I was trying to make the point that Pulsed Electric Field is not completely out of reach for some persistent cases.
As patients, we need to keep a sharp eye on current procedures and their consequences, and you have been doing that beautifully through your feedbacks on this forum.
Thank you, I understand the selectivity, I am curious though as to why the Male:Female ratio was so high. It just left me with a lot of questions.
I believe that traditionally trials have been male orientated. It is only recently that they have discovered that sometimes medication etc can be more effective for one sex or another.
Exactly - And my point!
Women have a more active immune system & more likely to develop autoimmune conditions & there is some evidence that ablation adversely affects those people. There are many examples of gender difference tolerance as women’s symptoms present very differently for quite a few conditions, including heart attack.
I have a dangerous intolerance to all heart meds so when a cardiologist told me I wouldn’t have AF if I took Bisoprolol I was fuming - I’m not one to dissolve into tears - he got both barrels.
All of our history is relevant - gender, sex, age, race and culture & is only now being recognised but the dominance of white, male, middle class thinking that mechanistic cause and affect eg: Ablate the rogue signals detracts from - what is the underlying cause? And how can we help you as an individual?
Trials are important, as are advances but I wish there was a little more equality in the reporting for whom a particular treatment would be relevant to.
I had a consult with my EP last week and we talked about this, sounds very exciting and could be a game changer for treating AF. He was very positive about the current trials in progress too, so it’s worth keeping an eye on.
Great that you discussed it with your EP. One statistic I got was that it is still 2-5 years away.
76 years old with A F
My recovery from my pulse field ablation April 15.
apixaban and hematuria 
shortness of breath
