Amitriptyline

[Dodie117]

Is anyone here on this? I’m having some sleep issues and my sister gave me low dose (10mg) to try !!

I know, not the best idea but only 2 tablets 10mg each.

Any experience/knowledge of this med in relation to af and apixaban. Google seems to indicate might cause palpitations but not clear.

[etheral]

Merck manual does list possible cardiac conduction effects such as frank arrythmia, tachycardia and is contraindicated in CHF. Sounds like a dedicated sleep p aids such as Ambien or a benzodiazepine would be a safer bet if you have afib or are over 60. Amitriptyline has strong anticholinergic effects that can exacerbate underlying heart conduction problems.

[Dodie117 in reply to etheral]

Thank you. That’s helpful.

[Kaz747]

I have been taking 10mg a night for about a year for postherpetic neuralgia. All my doctors (including 2 cardiologists and my EP) and my pharmacist have said 10mg is a very low dose and it’s not an issue with my other drugs or AF. I went off it for a while but the nerve pain returned and a sleep specialist I saw recommended restarting it. He said he often prescribes it to assist with sleep and for bed wetting or to help people who have to urinate a lot at night.

[Dodie117 in reply to Kaz747]

Thank you. That’s useful and interesting.

[mavisrich]

been on 10mg at night for many years. Cardiologist said he would prefer me to stop it but I said no because my back pain gets worse without it. My doc not worried because it is such a small dose but the difference in pain is remarkable.

[Dodie117]

Thank you. Interesting