The FDA is very clear that “there is no evidence from controlled trials that the use of amidarone favorably affects survival.” The agency makes it quite clear that amiodarone side effects are very serious so the drug should only be prescribed when other treatments have failed. The FDA also states clearly that patients should only be started on amiodarone in a hospital setting to reduce the likelihood of a life-threatening complication. We suspect that this advice is sometimes ignored No where in the prescribing information is atrial fibrillation mentioned as an approved indication forAmiodarone. It is intended for use only in patients with the indicated life-threatening arrhythmias because its use is accompanied by substantial toxicity.”
The FDA goes on to describe “potentially fatal toxicities” including lung damage, liver injury and heart rhythm disturbances.
• Lung toxicity is common (between 10 and 17%) and can be fatal; symptoms may include wheezing, difficulty breathing, fever, shortness of breath and coughing up blood. Pulmonary fibrosis is a very serious complication of amiodarone therapy
I hope people on this forum take notice of this advice. The FDA is the Food and Drug Adminstration of the United States.
I personally suffered severe lung toxicity after taking this drug for only a short time.