I put my first post on yesterday and thank you for replys. As I have been having a bad time with low heartbeat mostly around 40 and exhaustion Dr said that it was the Bisoprolol and today he said to come of it. It was a 1.25 dose so not high so hopefully everything will no OK if I come off it over the next week gradually. He said if AF kicked in take 2 doses together and then after 6 hours take another 2 doses. I have to see EP next week who also suggested a pacemaker last time I saw him privately in January, this time it isn't privately. Hopefully my heartbeat will go up and maybe not need to go down pacemaker route. Has this worked for anyone else on the forum, I am still on Rivaroxaban to help prevent stroke, I am getting great help reading the posts on the forum.