Any thoughts on this parasite killer being useful to trat advanced prostate cancer....
Ivermectin: Any thoughts on this... - Advanced Prostate...
Ivermectin
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rogerandme
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Yes, snake oil. No clinical evidence whatsoever.
Greetings Mr Allen. Nobody else has tried, so may as well be me; we have sparred before! I have Grade 1 PCa and take repurposed drugs including ivermectin. My PSA results have decreased and my MRIs are stable (see my profile and past "discussions" with you. BTW, Thank you for your opinion, you are very well-versed). I understand things although many on this group know some things more than me. However, I have a BS, MS, and a PhD in health science and complex systems from UK and USA.
I would like to hear your considered (not merely reflexive: "No clinical evidence whatsoever") response after listening to this Campbell-Makis discussion on repurposed drugs, specifically ivermectin, starting around the 40 mins mark. The earlier part is also useful to attain some respect. Dr Makis caught up with the repurposed drug revolution around 2022. However, I started the journey of discovery with my wife many years before when she had leiomyosarcoma and we discovered Jane McLelland, a major "stem cell" source of lived experience and wisdom for the repurposed drugs revolution, and also the Care Oncology Clinic (London) who standardised her discoveries into a genrealised 4-drug anti-cancer cocktail of atorvastatin, metformin, mebendazole (similar to fenbedazole), and doxycycline. Regardless, his summary stands for those wiling to learn...not sure if you are, as your response to the post was rather...constrained. Why? It doesn't matter really. What does is this:
youtube.com/watch?v=0gIYQCj...
Ivermectin is discussed here:
prostatecancer.news/2024/12...
I highly recommend the Netscape dramatized documentary "Apple Cider Vinegar."
Try the real deal above first. It's not a mere...drama. Metformin, statins, etc have real efficacy in cancer...and you know it.
Horrible idea with no science behind it
Just say no.
Yes. Don’t go there. There is no clinical evidence to support its use in humans as an anticancer drug and it is potentially toxic.
See my posts as I can show you you are wrong.
There is a lot of lab and animal work but no clinical trials in humans.
That does not mean it does not work but simply we have no evidence of effective or safety in the context of cancer.
Try adding water to cancer cells in the lab. It is a very effective cytotoxic - the cells die. Not recommended therapy for cancer.
Until someone somewhere does some decent clinical trial work my position remains - it is unproven both on safety and effectiveness grounds.
If you want to take it go ahead but don’t try to persuade others - that is snake oil salesmanship.
OK for tape worms and such like
While I was waiting for another treatment, I tried Ivermectin, Birm, Tumeric, mushrooms, etc. for over a month. I saw no change in rate-of-change in PSA. As far as I can tell, it did neither good nor harm.
John
What was your dose of ivermectin? And how often?
They never said. Dose is variable. Small for some, large for others. I know.
That's a pretty short interval for Ivermectin, but to each his own. My own experience is that IF it works, it only does so over a much longer period, and best in combo with regular treatment. But opinions do vary wildly.
I've comments numerous times about this. You can search my comments.
I've used but only recommend along with regular treatment, never instead of. The jury is still way out on things like Ivermectin.
Depends your stage. Grade 1 only this is reasonable (plus whatever supps you like). If more serious throw everything from the repurposed bag at it.
Dr Kathleen Ruddy and Dr Paul Marik are currently performing an observational study, similar to the Framingham Heart Study examining the potential of ivermection as an anticancer agent.
Here is a link to an interview that Dr Ruddy did. Purely anecdotal evidence at this point.
theepochtimes.com/epochtv/t...
As dhccpa mentioned, it is best to do in combo with normal treatment.
As this forum shows, there are no treatment options for many cancers for a complete cure.... there are no human studies on Ivermectin and Fenbendazole because there is no money in it for the pharmaceuticals, and the FDA definitely promotes that industry. My question for the naysayers is this. Most pharmaceutical drugs are also potentially toxic as well. The parasitic drugs are FDA approved for large and small animals, including shrimp. Why doesn't the FDA approve these drugs to treat cancer in animals? Or at least have them tested? I have lost two pets to cancer and had I known about the drugs at that time I would have used them to save my pets if possible.
The answer is obvious... if these drugs were approved for animals to treat cancer and worked, the FDA would be under pressure to approve them for humans or at least conduct human studies. Simple answer and a possible solution for a huge problem, with a lot of "what ifs?" That is why people do not trust our health care system. These are not only "parasitic" drugs... any more then aspirin is a drug for only headaches. They could be possible cures for cancer or a host of other diseases if the FDA would simply support studies. Until then, we will never know their true potential.
NO. Read New England J. Med October 20, 2021 on toxicity of unlicensed use of ivermectin in humans.
I stopped taking Fenben in early in July. My PSA at time was 5. Late Sept my PSA was 8.7 Dec 10th my PSA was 16. I'm back on Fenbendazole.
I finished Radiation in Sept 2023 and my PSA never got under 5. I had been on Fenbendazole 222mg per day for over 2 years.
Science or not it worked for me to keep my mets cancer under control.
It darn sure isn't going to kill you.
I'm back on it as long as I can live. I start. Chemo Monday. Might just add Ivermectian half cc today.
Interesting.... I found Fenben out of necessity. Six months ago I had a Holep procedure for an enlarged prostate. Despite an elevated PSA in the thirties for years, with no evidence of a tumor in my prostate, the follow-up biopsy showed cancer cells in the prostate. Since a Gleason scale was not possible due to the Holep procedure, my Urologist ordered a PET CT Prostate scan.
Before the scan was performed, my dermatologist found a tumor (the fourth) on my nose... an aggressive, invasive basal cell tumor with microtubules that had been missed during a previous Moe's procedure. Any radiation or radioactive exposure could turn the tumor into a "turbo" cancer, so any Prostate treatment had to wait until the basal cell was removed.
I had already had 3 flaps performed on my nose and another was not possible, so I would have to have a prosthetic nose, which I did not want. Besides, I am 81 years old and was a statistical "wash" as far as prostate treatment was concerned, so I opted or the "metabolic" route with FenBen.
It is now six months since my basal cell carcinoma was discovered, and the tumor has completely disappeared. My dermatologist is skeptical and wants another biopsy which I agreed to, and will be performed later this month. A comment will follow in a couple weeks!
So you attribute PSA rise halted to fenben? Did you notice any sides?
No side effects.... period. A blood test showed my ALT's were "slightly" elevated.
My friends mom had blood cancer. Went on no sugar diet which is really a low sugar diet and eating no foods with added sugar. And took ivermectin daily for 40 days. Cancer has been eliminated for 2 years now. I’ve read other stories as well about stage 4 cancers being healed but that one I personally can confirm.
I am taking on a holistic approach early. I am on the low sugar diet for 35 days taking 444 mg of fenbendazole, vitamin D, C, and zinc. Added tumerac and saw palmetto. I will be 72 hour fasting tomorrow. Research the cancer benefits but not recommended for bmi below 20.
Here is a link on alternative treatment if you are open minded but listen to your Drs of course :
onedaymd.com/2024/10/iverme...
I have now had 90 percent of the pain in my body reside since doing this. I am now holding from urinating every 20-30 mins to 2-3 hours so at least something is making me feel better. Started to feel it 30+ days into this.
I will be adding ivermectin next week at doses that needed to be calculated .
I get my Pscan Jan 16 and meet with oncology 1/28 so I am doing this before hand just to try something . I am going to have a psa test in 1-2 weeks with my last total 13.5/Free at 6 in early Dec. Gleason score was 10. Dr told me Monday expect stage 3 as best case based on the biopsy, advanced symptoms and bloodwork.
I am speaking with my sisters friend in 1-2 days that had stage 4 cancer all through his body, was given 6 months to live. He went on a 100 percent holistic regiment and healed himself and cancer free for 5+ years. Not sure exactly what all he did but will find out and post details.
Side note-My good friends wife was in stage 4 esophagus cancer, didn’t have much time left. Was healed by God in front me my eyes at a church service in Bethlehem PA at Assembly of God. I was there and everyone that attended felt the same electricity surge through their bodies when it happened. It was wild to witness. She is 8 years cancer free after her last scan showed 0 cancer. Have faith too. If you don’t know Jesus Christ, seek to. You never know what His plan is with you. Here is her husband talking about it and I am the “Jim” he mentions halfway through.
Things have improved quite a bit from when I was diagnosed nearly 25 years ago. When I had a second biopsy and nearly all of the cancer was gone and I told my Uro what I had done he held his hands out with palms facing me and fingers going left to right and told me it was all anecdotal. No science and didn’t want to hear about it. I met with Sam Denmeade two weeks for the first time and when he viewed the biopsies his remark was “incredible”. He then asked me every detail of my alternative journey and wrote it down as I gave it to him. I also found that there is a lab dedicated to fighting prostate cancer by managing the gut bacteria. He told me they have six stool donors at present. The name of that is named the Karen Sfanos lab. The director is Dr. Karen Sfanos.
I would suggest you look up Dr Makis substack. Lots of success there from actual use per his guidance. He pairs it with Fenben or Menben and sometimes SOC drugs. Before I decided on SRT after BCR, I used Fenben and it did lower PSA, but chose to go for cure possibility. My URO and good friend who is a good sounding board told me that when he went to Med School Loyola University that the standard of care for cancer were anti-parasite drugs!! Notice we still dont have any drugs that cure. Now seems lots of studies realizing the need for this. One thing to remember is that the GOLD STANDARD STUDIES standard is only there to protect Big Med. Most people on this and similar sites do not have the decade(s) to wait it out for that. In the meantime, i think the medical goal of "do no harm" is something to think about. Not advocating skipping curative SOC, but most users of the above drugs will see little to no side effects, and the cost is very low (hence the lack of interest/studies from Big Pharma).
Could you share more on how fenben helped you get PSA under control?
if you are really interested it is best to ask someone who has actually used it. I suggest you join the “my cancer story rocks” group on fb. You will first have to read some material by Joe Tippens. I have been following this group for about a year and have learned it helps some and does nothing for many. Kinda like all the SOC treatments. First google it and see what has been said in the few studies done.
Did you try it yourself? Any success?
I have not tried it yet and don’t know if I will. Like this group of cancer warriors that group has prayer requests for loved ones who lost their battle with cancer. I believe it helps some but it’s hard to tell how much since most are also doing or have done conventional treatment.
Actually works to lower my CEA timor.markers for two years now and has my oncologist amazed but does nothing for PCa or PSA because it's largely Androgen dependant.
No
This question keeps popping and i wonder what is driving it.
There is no sound clinical evidence that invermectin is of benefit in prostate cancer. Furthermore it is potentially toxic if misused. Please don’t take it.
This was misused during COVID in the US and it caused serious harm to some. The myth arose because in populations with high prevalence of intestinal infestation their health improved - but nothing to do with covid!!
It’s cheap, available at Tractor Supply, promoted by various influencers who target old men and works a bit like a Taxane by stabilizing microtubules and therefore messing with cell division (so it’s not totally without merit).
Add anecdotes where some have a drop of PSA because they use it together with other legit prescription prostate cancer drug and you’ll get people interested in it.
I was sick with Covid in 2021(First time catching it) I was getting worse and after 2 weeks was looking like I would be in hospital. Told the wife I am not dying on a ventilator, dump me in a park and let me die peacefully! Friend got me some ivermectin, applied the correct dose, I was 50% better after 24hrs and 100% better after a week. Did not take anything else. So I am convinced it saved me. As for the warnings from people hospitalised, as I have read, they took very high doses as they could not calculate the dose correctly. But all survived.
I understand your point of view. But we know nothing about the interaction of the drug with other standard treatments.
Hi again. Bear with me while I take a “critical” view of your Covid experience. As I am certain you are aware, the difficulty with interpreting your experience is that we cannot know whether you were just about to start improving anyway.
During Covid, UK NHS critical care doctors put together a national controlled trial of corticosteroids for sick patients critically ill with hypoxia. The trial recruitment was fast, the results positive, were implemented immediately and resulted in saving a huge number of lives.
Corticosteroids are cheap, and no commercial interest, so if the rationale (in this case damaging over production of inflammatory cytokines) and will are there, it can be done.
“the difficulty with interpreting your experience is that we cannot know whether you were just about to start improving anyway.”
I can guarantee this was not the case. I was ready for death. But each to their own, I know what worked for me. May not work for everyone.
I was just sharing my experience with it.
Respect. Understood!
I hear you brother, please read my reply to doctorseptic below.
I too had Covid with temps of 104 two nights and o2 levels of 88% and toughed it out at home. When I started getting better I certainly didn’t improve 50% in 24 hours at any time or 100% better after a week. It took months to get to feeling almost back to normal.
Are you suggesting that ivermectin might have helped you recover more rapidly??
Since you used the words “might have” I would have to say yes because to say no I would be saying that I don’t believe it possible. Remember when abiraterone was first tested it did not meet the targeted goal even though it was very close. And then there is that very small subset that responds incredibly well for a very long time. Why? That being said I doubt I have enough faith in Ivermectin to try it for Covid if there was something available that is tested and approved. That was not the case when I had it in Dec. 2020.
Sure I get your perspective. And of course tested Meds took time to come through.
I think though that when recommending a therapy that large numbers ( or even small numbers who might risk it from desperation) might be persuaded to use, one needs more than anecdote. The clinical controlled trials (uk and USA) that were done in Covid did not show significant clinical benefit for ivermectin, and more to the point, the uk study did show clear benefit for budesonide, an inhaled corticosteroid, in one arm of the trial.
There is no reason why such a study could not be done for ivermectin inPCa! It requires interest, a good underlying rationale and willingness to act.
There are some naturopathic doctors who promote colonics to clear the digestive tract of harmful bacteria, parasites and fungus. I used this 24 years ago when first diagnosed. My Uro told me it was anecdotal and not backed by science. He was a no name doctor who went by the SOC and told me I needed surgery. Two weeks Dr. Samuel Denmeade reviewed my 2000 and 2002 biopsies. There was an improvement that Dr. Samuel Meade referred to as incredible. I then told him everything I did which he wrote down. I told him I had pics of stool at beginning of cleanse and after colon was clean which required 2 cleanses this last time. He wanted to see them and asked me to describe my stool when not cleansing. He then told me that John Hopkins had 6 stool donors and a lab dedicated solely to studying the effect of gut bacteria on Pca. The lab is named the Karen Sfanos Lad. So what was anecdotal 25 years ago is now science. Now, isn’t that just special? Some folks are fine with waiting for others to find the answers and some “get er done” on their own.
I’m on 96 mg of ivermectin daily and 444 mg daily fenbez. Been on the fenbez 4 weeks. Ivermectin only 4 days. Also on keto for cancer diet that by itself which 100 percent healed my friend of stage 4 cancer in lungs, bones, and pancreas given 3 months to live. He is 8 years cancer free and did it by diet alone. So it is possible. He said I need to get my GKI to under 3 and keto it there and control protein intake to limit glutamine to feeding cancer.
So I decided to do the same diet and add parasite killers. My GKI is down to 10 now. I measure daily
Had my petscan last week after 10 Gleason score in Dec. To everyone’s surprise, the PC was only in the Prostrate. My Dr told me to expect it to be at least in bladder.
I had extreme pain and lumps in neck at left/right lymph nodes, lower right back and lower right abdomen in 2024 into early Jan.
All pain in now gone since doing my own protocol. My urination patterns also dramatically changed. I go all night without peeing vs 5-7 times before this protocol.
PSA went from 6 to 10 in 18 months then to 13.3, 8 days later with Free psa at 6. I get next psa test tomorrow. If it is lower by 20 percent, I will continue. If it rose, then will rely on oncologist and throw in the towel. My plan was to do radiation anyway and not take out my prostrate. I had a window of time to experiment but my prostate mri is in 2 weeks and next oncologist is soon after.
Please update us on your latest PSA results!
Will do. Getting it next Tuesday/wed now by oncologist. Was 12.74 last week. 13.36 in Dec. so if it’s down again in just 2 weeks, then it’s working imo.
Oncologist wants me on combo radiation therapy with ADT. I’m not doing ADT if it’s just still in my prostate. Side effects are not worth it for me. I’ll take my chances with radiation alone if my concoction fails. But she told me it’s definitely stage 3 as it stands now
I haven’t felt this good in over a year. And it’s nothing big pharma did.
Thank you for replying. There is an awful lot of potential snake oil talk in this series of posts.
People should read New England Journal of Med October 20, 2021 on toxic reactions from unlicensed use of ivermectin. It is not stuff to play around with.
I am as sceptical as the next guy about big pharma but a bit of critical thinking is also needed about the risk of following anecdotes. I can’t say it might not be a useful drug, but it requires controlled studies to demonstrate whether it is better or worse than placebo. There is government and charitable funding for repurposing of existing drugs, big pharma is not the only source of funds - but there has to be a good preclinical evidence base before considering its use in humans for treatment of cancer.
Isn’t clinical trial the hundreds taking it and recording their results publicly? Or does it have to be controlled by big pharma! Whom, will never do trials on ivermectin because no money in it. They don’t want it to work .
I’m my own clinical trial. Gleason 10 score. And my psa reversed .62 with most aggressive prostate cancer on a week of ivermectin. Must be snake oil.
Next psa next week and will record. Still in 96 mgs of ivermectin. Minor vision side effects first day as expected that went away in 3 days like Dr Makis said. Lowered Fenbez to 500 mg 3x week from daily.
As I explained in my post, big pharma does not have to be involved to run decent clinical trials and there are other sources of funding. A recent example was the trial of corticosteroids (a cheap drug) in very sick Covid patients setup by a collaboration of intensive care specialists across the UK which was done quickly, was successful and saved a lot of lives. You can look it up.
I honestly don't know whether ivermectin helps or not. To the best of my knowledge there a large number of in vitro cell studies and animal studies, many suggesting it might be of benefit, but none on humans.
Frustating I agree and if you are very keen why don't you discuss with your doctor doing an N=1 study on yourself - one model (using yourself as the control), is to have precise periods on and off the drug with observations after each period to see whether there is really a noticeable difference/trend in clinical measures. You would need to agree in advance what represented a statistically significant change. There is a thought for you. Test the snake oil!
I wish you well - good luck and I hope it continues to work for you.
Good idea. Doing it with my VA Dr.
Dr John Campbell on YouTube has run several videos specific to IVM and also, it's relationship with FenBen. Apparently there has been thousands of studies of IVM & cancer done in Europe with positive results.
youtube.com/watch?v=DX0hqmg...
thanks for the video link
John Campbell just did a long interview with William Makis on ivermectin and other repurposed drugs for cancer, Feb 2025. See also Paul Marik's book Cancer Care which is now #1 Bestseller in Health on Amazon but pre-print is free: imahealth.org/reviews-and-m...
Go to Google scholar and type Ivermectin cancer. Hundreds upon hundreds of studies, Pubmed, Wiley, NIH, you name it. Read some of them. Is it because all those people were bored and didn't have anything better to do? I don't think so. Also, the university of Glasgow is conducting a study on another parasite medication, Mebendazole. You know those folk don't have the means nor the lack of common sense to screw around with things that don't have a minimum possibility of working. Study it and reach your own conclusions. Note that many of the meds in the studies potentiate the existing SoC meds
There are some natural supplements that lower androgen that is key with Prostate Cancer. IVM is not one of them.
Reducing glucose and glutamine is key. Blocking testosterone doesn’t cure it. Just slows it down and stops spreading.
Plenty of evidence: anecdotal, and observational and pre-clinical trials; also hundreds of lab studies. John Campbell just did a long interview with William Makis on ivermectin and other repurposed drugs for cancer, Feb 2025. See also Paul Marik's book Cancer Care which is now #1 Bestseller in Health on Amazon but pre-print is free: imahealth.org/reviews-and-m...
Ivermectin discussion around the 40 mins mark:
Please don’t correspond with me again.
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Any body have any experience or views on Ivermectin and cancer?
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7505114/
