Since you were diagnosed with PCA, ha... - Advanced Prostate...

Advanced Prostate Cancer

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Since you were diagnosed with PCA, have you caught colds more often or less?

Mascouche profile image
24 Replies

Hey all,

Just wondering if I am an exception or if it means something, but I've realized that over the past 5 years, I probably gotten a gotten only once or twice. Yet my son, daughter and my wife catch cold 2 to 3 times a year every year and we are all under the same roof.

I'd expect cancer to weaken my immune system and that I'd be having colds more often than my family does but somehow its the opposite. Wondering what mechanism might be at play that makes me, an advanced cancer patient under treatment, get sick less often that 3 healthy people.

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Mascouche profile image
Mascouche
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24 Replies
Jpburns profile image
Jpburns

I have not had a cold since my diagnosis (November 2023)… until this last Labor Day. I got a ridiculous head cold with lots of nose blowing and congestion. Then it went away in under a week, but came back as bronchitis, with a persistent hacking cough (For nearly a month). I’m just getting over that.

So the short story is… don’t be too cocky.

London441 profile image
London441

Definitely less. Although counterintuitive, I ascribe it to the combination of testosterone suppression and just getting older. Both have changed my immune response in general. Sick less often since I hit my fifties, and even less since diagnosis.

dhccpa profile image
dhccpa in reply toLondon441

Ahhh, the little-known benefits of PCa!

NickJoy profile image
NickJoy

I've noticed the same thing with my husband who has not been touched with a cold since he was diagnosed nearly 4 years ago - this despite the fact that our school aged daughter has brought home several nasty bugs which have really wiped me out....

schlauchkopf profile image
schlauchkopf

Same here - going on 15 years since diagnosed, and I can count on one hand the times I've had a cold - and even then, I'd get over it in about 5 days.

j-o-h-n profile image
j-o-h-n

It's your body odor......... keeps all those sick people away..........

Good Luck, Good Health and Good Humor.

j-o-h-n

Kaliber profile image
Kaliber in reply toj-o-h-n

Rotflol

Mascouche profile image
Mascouche in reply toj-o-h-n

Not those with stuffy noses :)

TuffNuttoCrack profile image
TuffNuttoCrack

My new metric is days since last infection (days since we have had an accident for comparison). Just told a few days ago first and only chemo likely wiped out immune system two years ago. When I begged for more chemo, oncologist said infection will kill you before cancer. After having two hospitalizations with pneumonia (a deadly one acquired from the hospital during a routine procedure) and two cases of RSV in last two years six months apart, I believe her. One RSV occurred just three days after getting the vaccine. My answer to infection, wear an N95 mask in public places if you are immunocompromised. Haven’t had an issue in half a year now and my goal is to stay away from the hospital completely for years as it’s full of sick people. Yeah I’m as tough as anyone out there but infections carried from other people are my Achilles Heel. Don’t let a contractor come in without you being masked up if you are susceptible!

Mascouche profile image
Mascouche

I see that, aside of those whose immune system was weakened by chemo, I am far from alone in getting way fewer colds after diagnostic.

Does anyone have a theory as to why that might be? Here are 3 that have crossed by mind but I have no clue if any of those 3 is close to the truth.

Is it because our immune system is already on high alert due to cancer and it nips colds viruses in the bud as soon as encountered?

Or, to the contrary, is our immune system weakened enough from fighting cancer that it does not put up enough of a fight for cold symptoms to be perceptible (assuming for example that a runny nose is not due to the virus itself but to our immune system trying to flush out the virus)?

Or do cold viruses fail to take hold on bodies that have cancerous cells?

Maxone73 profile image
Maxone73

Apart from cancer, I have always had a good immune system, last year, after my third or fourth docetaxel session, my wife and the kid got the flu, we have always slept in the same bed and been together as usual. I did not get it, nor a cold. Maybe it's because of one of the supplements I take, but it seemed like docetaxel did not touch my immune system at all 🤷‍♂️

85236442968 profile image
85236442968

Mascouche

By chance do you have grandchildren that have got out/aged out of day care. during this time???

Day care is a petri dish environment.

I am with my grandchildren quite a bit and noticed the change as they aged out of the day care system.

Not only does it appear they were sick less often, so were Grandma and I.

Mascouche profile image
Mascouche in reply to85236442968

My children are adults but still at home. Everybody passes viruses around where they work so when they come home, they end up infecting my wife as well but not me for whatever reason :)

Eadgbe profile image
Eadgbe

Interesting observation. Although my PC wasn't advanced, aside from sepsis from a biopsy, I've avoided the colds, too. I had 6 months of Eligard and 45 sessions of RT. I am around a lot of carriers of infection (kids) also. Diagnosed in 2023.

London441 profile image
London441

Older people who aren’t outright immunocompromised or in poor health supposedly get colds and other viruses less often, generally due to immunity buildup. Maybe! . But many of us also just become less relentlessly social.

When I was young being in (and out of) school, hanging out with friends and not paying much attention to hygiene was standard. Later I became a musician, went to clubs a lot when I wasn’t performing . I later worked in restaurants, in schools, volunteered in hospitals and other institutions. Played a lot of indoor sports in winter. All while maintaining robust dating life accompanied by some very flexible morals. I got colds probably 3 or 4 times a year.

The pandemic permanently altered social life for a lot of us too obviously.

Getting older for me may have resulted in increased immunity, but I also believe both my previous lifestyle and testosterone itself were truly double edged swords in quite a number of ways.

VHRguy profile image
VHRguy

Since I retired 5 years ago from an office / engineering lab environment, I've maybe had one or two colds that entire time. I did get covid a couple years ago, but got over it quickly (no vaxes either, but that's a whole different discussion).

I haven't been sick since then, and it's over 2 years now. We're still quite social, but probably take personal hygiene more seriously. I'm over 11 years now since my G9 dx and treatments, and feeling quite blessed!

Mascouche profile image
Mascouche in reply toVHRguy

Even with regards to Covid, all 3 other people got it at least once if not twice. I did not catch it at all. Or if I did, I was asymptomatic.

VHRguy profile image
VHRguy in reply toMascouche

The only people I know who had covid more than once had been vaccinated. There is some discussion about the impact of the vax + boosters sequence affecting the robustness of the immune system responses. Again, that's a whole different discussion, but overall it is really interesting how seldom some of us catch colds now!

TrashPanda72 profile image
TrashPanda72

100% more often… I now have a perma sinus infection. And if you have the flu - I’ll be sick in 12-18 hours… it is like I have no immune system!

Mascouche profile image
Mascouche

Perplexity.Ai has nothing solid as to why several of us appear to catch fewer colds concrete but a few ideas about this.

***

Heightened Immune Response

Some cancer treatments may temporarily boost certain aspects of immune function, potentially providing enhanced protection against common infections like colds. The immune system may be in a more activated state overall while fighting the cancer.

Increased Health Awareness

After a cancer diagnosis, patients often become more attentive to their health and may be more likely to notice even minor symptoms. This heightened awareness could lead to early intervention for potential infections.

Cytokine Effects

Some prostate cancer treatments can affect levels of cytokines in the body, which play a role in immune responses. These changes might inadvertently provide some protection against common viral infections.

Hormonal Influences

Androgen deprivation therapy, a common treatment for prostate cancer, alters hormone levels in the body. These hormonal changes could potentially have indirect effects on immune function

SteveTheJ profile image
SteveTheJ

I was never very susceptible to a cold and cancer has not changed it.

garyjp9 profile image
garyjp9

Mascouche, yes I have noticed the same, with no explanation for it

mababa profile image
mababa

Mascouche, speaking only from personal experience, I don’t believe having PCa has anything to do with catching more or fewer colds. I had undetected PCa for at least 5 years before starting any treatments. Never been healthier and cold free. But, what I will say is that since starting ADT (Orgovyx) in Feb 24, I’ve had at least three significant colds that seem to last forever. I think lowering one’s testosterone adversely affects one’s immune system. Just my opinion.

32Percenter profile image
32Percenter

I notice this too. I was the "snotty kid" several times a year before, but I barely get sick since my diagnosis and chemo. This is despite my bloods showing low immune markers.

I think a lot of it has to do with avoiding simple sugar since my diagnosis (or taking it only in moderation as an occasional treat). Sugar depresses your immune system. My taking a tablespoon of black cumin seed oil daily for the past two years may be a factor as well.

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