Mediterranean Diet Is Associated With Lower All-Cause and Cardiovascular Mortality Among Long-Term Cancer Survivors
J Am Coll Cardiol CardioOnc. Jul 02, 2024. Epublished DOI: 10.1016/j.jaccao.2024.05.012
“High adherence to a traditional MD was independently associated with a substantial reduction in all-cause mortality rates among cancer survivors, specifically in cardiovascular mortality. The latter observation is relevant because patients with cancer are considered a high cardiovascular disease risk population4 because of shared modifiable risk factors and, potentially, molecular mechanisms of disease, as postulated by the “common soil” hypothesis.5 The MD is abundant in foods that are natural sources of polyphenols, which are bioactive compounds with well-established anti-inflammatory, antioxidant, and antitumor activities that may be relevant not only to cancer onset and progression but also and possibly even more to cardiovascular mortality prevention.”
“Lack of a significant association with cancer mortality could be due to the different types of cancers included and the multifaceted nature of cancer progression and recurrence, which is strongly influenced by non-nutritional factors (eg, diagnostic and prevention strategies) varying substantially across socioeconomic strata of the population.”