Better chemo administration technique, takes into account each individual patient

[Maxone73]

“People with the same body surface area could have very different heights and weights, could have very different muscle masses or genetics, but as long as the height and the weight plugged into this equation give the same body surface area, their dose is identical,”

news.mit.edu/2024/closed-lo...

[God_Loves_Me]

What's the best way to lower risk of Neuropathy ?

[Maxone73 in reply to God_Loves_Me]

Neuropathy? They say ice on feet and hands. My MO said it works only for you hair. I did nothing but it was very mild and for few days in my case.

[skiingfiend in reply to God_Loves_Me]

The Impact of Peripheral Cooling on Chemotherapy-Induced Peripheral Neuropathy: An Integrative Review

ncbi.nlm.nih.gov/pmc/articl...

Chemotherapy-induced peripheral neuropathy (CIPN) is a prevalent, potentially long-lasting side effect of select chemotherapies. It contributes to suboptimal chemotherapy dosing, and its symptoms negatively impact patients’ quality of life. To date, interventions to effectively prevent this toxicity have not been established, and interventions to treat CIPN have produced only modest results. The purpose of this integrative review is to examine the impact of regional cooling applied to distal extremities on the severity of CIPN. A literature review was performed using SCOPUS and PubMed databases. The search was not restricted by date but was restricted to English language. Forty-two articles were identified in the search, and six were included in the review after applying inclusion and exclusion criteria. Results related to protective effects from peripheral cooling against CIPN were variable. Four out of six studies demonstrated benefit of peripheral cooling in reducing the severity of CIPN. There was evidence to suggest that applying a relatively greater degree of cooling compared with a lesser degree may confer benefit in reducing the severity of CIPN. Both direct application of cooling and use of compression to achieve fingertip cooling showed potential benefit.

At this time, there is insufficient evidence for or against the use of peripheral cooling to prevent CIPN.

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I use ice socks and gloves during my chemo in 'why not - what have I got to lose' mode.

[HikerWife in reply to God_Loves_Me]

Ice on feet and hands, also sucking ice chips. My husband had zero neuropathy, Your MO is incorrect.

[skiingfiend]

Interesting - but could most of the benefits be achieved by better dosing algorithims and daily sampling, resulting in minimal incremental cost.

The thought of another needle in addition to the infusion needle - drawing blood every 5 minutes for analysis does not appeal to me very much.

Cheers

[Maxone73 in reply to skiingfiend]

well, they tested on a kind of chemo that is administered via a 46 hours long infusion, I don't think it would make much difference for them!

[j-o-h-n]

Shit......... if someone looks like me, body wise naked...........I'd rather bite the bullet and then load it into my Glock....(Shots fired.... shots fired)...

Good Luck, Good Health and Good Humor.

j-o-h-n

[Justfor_]

"Louis DeRidder, an MIT graduate student, is the lead author of the paper..."

Is MIT renown for its medical school or its engineering one? (rhetorical question)

I am in the 2.5 years mark of adjusting, on a monthly basis, my Bicalutamide dosage by tracking my PSA. I didn't have the need to read any relevant paper, it was just too obvious...

healthunlocked.com/prostate...