I have read on here and it’s just an observation from reading bios of different patients “ we treated the bone Mets and psa exploded afterwards “.
my question is: could the reason for that being the effects of the SBRT or whatever kind of radiation to the Mets ?
More than once I have noticed that. I hope I am wrong. This makes me worry about taking the route of the wait and see until psa rises , do a psma, find the Mets and treat with radiation INSTEAD of just starting systemic therapy (ADT).
Tough call and for me comes down to if I believe the Drs that this treatment increases OS. You may need to wait until it hits 2 to make a decision anyway unless they consider a 2nd recurrence different than a first. I guess the idea of anything near my skull kindnif freaked me out a little so choosing to get radiation wasn't that hard. I had no issues the first time so just hoping the same this time around but I know there are risks.
Hmm. It could happen because of "repopulation." Repopulation, one of the ways in which cancer can elude radiation, means that when radiation kills some cancer cells but leaves many behind, the remaining ones now have access to space in which to expand and access to nutrients and oxygen that the other cancer cells had deprived them of. Paradoxically, the tumor can then grow faster than it ever would have before the treatment. I'm not saying this happens, I'm only saying it is a possible hypothesis. Until we learn more, ADT is the only tried-and-true way to treat PCa.
safely radiate the ones you can see or are causing pain/problems
starve the rest
take a break
rinse and repeat
Hope they come up with something to eradicate it all.
If oligometastatic direct radiation of mets may delay the start of ADT. There is not evidence that will prolong life.
Radiation treatments.
Time to radiation treatment
Advice on radiation treatment?
Radiation as a first-line treatment
Radiation treatment - 13 years
