darolutimide: my husband has started... - Advanced Prostate...

Advanced Prostate Cancer

22,874 members28,485 posts

darolutimide

Tomatogardener profile image
6 Replies

my husband has started darolutimide. Has it made any of you more fatigued than just the lupron?

Written by
Tomatogardener profile image
Tomatogardener
To view profiles and participate in discussions please or .
Read more about...
6 Replies
GP24 profile image
GP24

In this study 15.8 % of the patients who took darolutamide reported fatigue compared to 11.4 % of the patients on lupron.

Exercise is best to fight fatigue.

nejm.org/doi/10.1056/NEJMoa...

j-o-h-n profile image
j-o-h-n

darolutimide = NUBEQA

I will be taking this expensive med soon so I'll post if it makes me more fatigued.... Husband, Good going man.....

Good Luck, Good Health and Good Humor.

j-o-h-n Thursday 02/23/2023 7:02 PM EST

Gl448 profile image
Gl448

I’ve been on NUBEQA (darolutimide) for two months, I did not notice any additional fatigue or other side effects over and above Eligard (Lupron).

Aprilshowers2024 profile image
Aprilshowers2024 in reply toGl448

GI448...STARTED DAROLUTIMIDE JUST OVER A MONTH AGO IN CONJUNCTION WITH LUPRON DEPOT...ALT AND AST GONE MAD....ANYONE HAVE A COMMENT

ColinBray profile image
ColinBray

Yes.And certainly more nausea !

Col B

Aberdeen911 profile image
Aberdeen911

I had more nausea the first month but that past. The fatigue is there but not sure it is from Lupron or the added Nubeqa. One additional issue I have ran into is increased neuropathy in my extremities. They started me on Gabapantin to fight it, one med to fight side affects of another and so on. Really tired of it.

Not what you're looking for?

You may also like...

Darolutimide as monotherapy

I know there has been a phase 2 trial (EORTC-GUCG 1532 trial) testing the efficacy of Darolutimide...
RugbyVLS profile image

Nubeqa (Darolutimide) mono-therapy update

I have been on Nubeqa as a mono-therapy now for just over 3 weeks, and the first blood draw was...
joeguy profile image

Has anyone had side effects from Nubeqa/Darolutimide?

Has anyone had side effects from Nubeqa/Darolutimide? If so, what were the side effects. No side...
GeorgeGlass profile image

NUBEQA (darolutimide) as MONOTHERAPY (no lupron or similar)?

I’ve seen two posts today in a couple of threads stating that they’re currently on NUBEQA, or will...
Gl448 profile image

Advice

My brother -in - law, has primary prostate cancer ,it has spread to liver , kidneys, lymph nodes,...
Sergison profile image

Moderation team

Bethishere profile image
BethishereAdministrator
Number6 profile image
Number6Administrator
Darryl profile image
DarrylPartner

Content on HealthUnlocked does not replace the relationship between you and doctors or other healthcare professionals nor the advice you receive from them.

Never delay seeking advice or dialling emergency services because of something that you have read on HealthUnlocked.