My recent Guardant liquid biopsy report detected PIK3CA Amplification. There are currently no FDA approved therapies available. Appreciate input.
PIK3CA somatic mutation identified vi... - Advanced Prostate...
PIK3CA somatic mutation identified via liquid biopsy
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HopingForTheBest1
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The only open clinical trial I know of is this one:
clinicaltrials.gov/ct2/show...
Copanlisib is an PI3K inhibitor, already FDA-approved for follicular lymphoma.
Discuss about ipatasertib which has been used along with abiraterone in patients with PTEN loss which also affect the PIK3 pathway
Hello - I have a double PIK3CA mutation and started the Tapistry trial last week at Mount Sinai as i'm eligible for inavolisib (GDC-007), which has shown efficacy: mountsinai.org/clinical-tri...
Thanks for this info. Do you know which cohort are you in?
Tapistry Cohort H. See: westcancercenter.org/trials...
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FINAL DIAGNOSIS
ISCHIUM, RIGHT, CT-GUIDED CORE BIOPSY:
- METASTATIC PROSTATIC ADENOCARCINOMA....