what does this really mean in PCa term ? PSA 55 initally, within 30 days 100.
Gleason 9, but only 2 proximal lymph nodes seen on MRI.
All CTs , bone scan shows no other mets sites. Thanks.
what does this really mean in PCa term ? PSA 55 initally, within 30 days 100.
Gleason 9, but only 2 proximal lymph nodes seen on MRI.
All CTs , bone scan shows no other mets sites. Thanks.
Sounds like you have no distant metastases your disease is likely curable
An MRI isn't enough. You have to have a bone scan/CT and a PSMA PET/CT.
Try to get a PSMA PET/CT to see if the cancer is localized only in the pelvis.
Positive lymph nodes in the pelvis are not considered metastasis. (N1 stage)
If there are not distant mets (outside the pelvis),(M1 stage) treatment with radiation to the prostate and the whole pelvis lymph nodes plus 2 years of ADT and abiraterone may offer a good control of the cancer and it may be a possibility of "curing" the cancer.
As I remember from the studies, oligometastatic is defined as 5 or less mets in a vertical axis to the prostate-- which I assume means confined to the spine. This would exclude distant mets off that vertical axis, e.g. to the ribs away from the spine.
I believe the number of mets considered to be oligometastatic originally was 3 or less, this was soon expanded to 5 or less, and now may be considered up to 8 or 10 mets by some doctors. How many more more mets might fall into that definition in the future is any ones guess.
Also, as I understand it, mets in the pelvic lymph nodes are not counted, so the limit of 5 (or 10) is for mets in lymph nodes outside the pelvis, or in bone, or in other organs. I've never seen the counting rules stated explicitly anywhere, but maybe they're in the latest APCCC or NCCN guidelines.