I77 Lu PSMA - I&T V

[kathim]

Good Morning,

Wondering is anyone is familiar with this therapy? Comments or suggested reading would be helpful.

thanks so much

kathi

[tango65]

I had this therapy in 2016 at the Technical University of Munich. The efficacy and side effects of this ligand is similar to the PSMA 617. There is a theoretical advantage since the I&T ligand has a smaller molecule which could facilitate the penetration of the ligand and the Lu 177 into the cancer cells.

[kathim in reply to tango65]

hello,Thanks for the response. I am unfamiliar with PSMA 617; what were your side effects? And was your treatment successful? Thank you

[tango65 in reply to kathim]

Side effects minimal. Some fatigue for 24 hours. Treatment was successful according to 6 PSMA PET/CTs done since 2016. Lu 177 PSMA 617 is the most common ligand used to treat PC, it is the one called Pluvicto by Novartis in the USAnovartis.com/news/media-rel...

[kathim in reply to tango65]

Much appreciated!