Unusual Xtandi side effect or coincidental ?

[Bjry]

I've just syarted my 3rd week of Xtandi -without any side effects until yesterday and much more so today. Both feet are now covered with red blotches and I have red spots over both legs and my chest. This sort of thing is listed as a possible allergic reaction to Xtandi but my MO says in 20 plus years of practice he has never seen it. At present I'm keeping on full dose but will stop if other significant effects occur. Anyone else experience this?

[Tall_Allen]

I've heard of it with Erleada, but not Xtandi. How are your liver enzymes?

[Bjry in reply to Tall_Allen]

Thanks. I have another blood test next week and I will check with MO when I speak to him later. Liver has never been mentioned as an issue before. It's looking more like a coincidental linkage and I need to look for a distinct cause.

[Momtonani]

My significant other had a serious reaction to Xtandi including the rash all over his body and swelling of his face. Had to do mega doses of steroids and allergy pills for a few months. Also had to carry an epipen just in case. He was pretty miserable for a few weeks while waiting for it to clear his system. He had started it after a couple doses of Xofigo. So we are not sure if that had something to do with the allergic reaction. We also could not find any information about such reactions. 🙃

[j-o-h-n in reply to Momtonani]

to Mom or nani,

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j-o-h-n Friday 06/17/2022 7:00 PM DST

[Momtonani in reply to j-o-h-n]

I have been meaning to…..

[j-o-h-n in reply to Momtonani]

Thank you.... we need your input so keep posting...

Good Luck, Good Health and Good Humor.

j-o-h-n Saturday 06/18/2022 12:51 PM DST

[Bjry in reply to Momtonani]

Far more serious reaction than mine. Did he have to stop Xtandi? At present I am keeping on but if a more serious reaction happened I'd stop.

[Momtonani]

He did have to stop. He took it for a couple of weeks and slowly started having a rash and itching. We weren’t sure at first if it was the Xtandi or not since there was no initial reaction. After he woke up in the middle of the night with a huge swollen lip, we made the trip to the ER.