Is there a study or paper that looks at possible overall survival if a certain point is reached after diagnosis.

[Jlcwonderboy]

I’m probably not explaining this very well, but I’m curious to know if anyone is aware of anything that has looked into possible life expectancy for advanced prostate cancer if say, a patient is still alive five years after diagnosis (and therefore could be said to be responding well to treatment).

Is it understood that if you reach 3 years post diagnosis you are more likely to reach 5 or 6 years? And if you reach 5 years post diagnosis you are more likely to survive 10 years etc?

Common sense would suggest this is probably the case because if you reach these milestones it is likely you treatment has largely been effective and successful and that it is probable this will continue to be the case (or at the very least you still may have certain treatments that are still available you).

I hope that broadly makes sense. Thanks

[Pleroma]

There are many variables in APCa treatment, but I think it is more of a bell curve with 5 years being at the top and progressing downwards from there if you know what I mean.

[swwags]

Are you referring to Nomograms? Sloan Kettering has a tool but it's a predictor based on historical data, so in a sense, the data can be old as new treatment come along. It's not quite what you're asking but maybe some help?

mskcc.org/nomograms/prostate

[GoBucks]

There are no guaranties in life except at The Men's Warehouse. That's an American joke.

[TeleGuy]

I was doing more reading tea leaves at the beginning of my journey, but the following study gave me some good cheer (only applicable at the beginning). Maha Hussain et. al. looked back at their CADT vs IADT paper and found that the PSA response at month 7 to intermittent ADT was prognostic for overall survival. I don't see how this would not be predictive from both CADT and IADT as it's just measuring response after the first 7 months of therapy:

ascopubs.org/doi/10.1200/JC...

What they found is that you qualify as low risk if your PSA is <0.2, leading to a median survival time of 75 months, if it is 0.2-4.0, you are at intermediate risk with median survival of 44 months, and high risk if it's >4.0 with a median survival of 13 months. Remember that your mileage will vary because your disease may be more or less advanced than those in the trial.

[j-o-h-n]

We on the technical team use small pieces of paper with numbers written on them and an old hat............A young maiden in a bikini usually is the picker......(note we place the hat on the floor for obvious reasons)....

Good Luck, Good Health and Good Humor.

j-o-h-n Thursday 09/23/2021 11:39 PM DST