SBRT Post Treatment

[Sunfire]

PSA started at 6.60. Then G7 (3+4) after monotherapy post treatment SBRT 6 mo. was 3.30 and 12 mo. was 1.43 and now 18 mo. is 1.11. Trending down but shouldn't it be closer to nadir .05 at 18 mo. post treatment?

[Tall_Allen]

Mine took 4 years to reach nadir, which is 0.1. Why do you think your nadir will be 0.05? That would be VERY unusual.

[Sunfire in reply to Tall_Allen]

I meant .5 that is considered nadir correct? Didn't realize it could take up to four years. I was told it should be reached within two years post rads treatment.

[Tall_Allen in reply to Sunfire]

It will take however long it takes. Nadir means the lowest point PSA reaches, It isn't an absolute number,. It's whatever your prostate reaches. This isn't physics, it's biology.

[Sunfire in reply to Tall_Allen]

Thanks then any amount of trending down is good!

[doc1947g in reply to Tall_Allen]

After 4 months post VMAT-RT I reach my PSA nadir = <0.01 μg/L.

9 monts later May 2021 PSA went to 0.04 μg/L.

[Spyder54]

Your trend is excellent! Many have posted here on HU, that slower to nadir often equates to a longer OS. Lets take that as another positive. I too am slowly coming down. Will take all the Wins we can get!Best,

Mike

[Sunfire in reply to Spyder54]

Thanks Mike. Let's keep that downtrend going! All the best

[drmoose]

recent study on this issue doi.org/10.1016/j.urolonc.2...

[NotDFL]

As first stated by Tall Allen, the trend looks quite promising.