CRISPR: medpagetoday.com/neurology/... - Advanced Prostate...
CRISPR
Cut and edit DNA. In-Vivo Phase 1 . This could and should be HUGE!
I agree.
Thank you for posting! I'm hoping very much for this!
cancercenter.com/community/...
Not perfect, but promising. More for immunotherapy, and leave solid tumors to SABR!
CRISPR clinical trial for cancer
America’s first clinical trial using CRISPR for cancer was launched at the University of Pennsylvania in 2019, and it’s still ongoing. In that trial, researchers are testing an immunotherapy treatment using a patient’s genetically modified immune cells.
The immunotherapy treatment uses modifications to T cells—the immune cells that may be able to detect and kill cancer cells. CRISPR was used to remove three genes that may interfere with or limit the cells’ ability to kill cancer.
In one patient with multiple myeloma and another with a solid tumor, the treatment stopped tumor growth at first, but then the growth resumed. Still, the study may hold some promise, especially for the treatment of solid tumors, Edward Stadmauer, MD, a professor at University of Pennsylvania who leads the clinical trial, tells the National Cancer Institute’s Cancer Currents blog. “Solid tumors have been a much more difficult nut to crack with cellular therapy," Dr. Stadtmauer says. "Perhaps [CRISPR] techniques will enhance our ability to treat solid tumors with cell therapies.”
