Just a FYI for a new video from Dr Gr... - Advanced Prostate...
Just a FYI for a new video from Dr Gregor, citing a study determining fat drives metastasis of cancer cells.
I posted on palmitic acid 4 years ago [2]:
Greger would put us on a low-fat / high-carb diet, but that would only increase palmitic acid.
We make the stuff.
"Palmitic acid ... is the most common saturated fatty acid found in animals, plants and microorganisms." [1] - that includes humans.
"Excess carbohydrates in the body are converted to palmitic acid." [1]
"Palmitic acid is the first fatty acid produced during fatty acid synthesis and is the precursor to longer fatty acids. As a consequence, palmitic acid is a major body component of animals. In humans, one analysis found it to make up 21–30% (molar) of human depot fat" [1]
-Patrick
As Patrick notes, it is a mistake to think a cancer that depends on fat must be depending on DIETARY fat. As well as dietary carbs potentially contributing to the body's production of its own fats, the other essentials of de novo lipogenesis are amino acids. So high-protein diets or high-carb diets may make you fatter (and potentially promote metastasis?) as much as some high-fat diets, if not more.
One thing that might NOT promote excessive production of fatty acids by the body would be... dietary fat! That is why ketogenic high-fat diets can work to LOWER triglyceride levels, and high-carb diets that are low in fat can work to RAISE triglyceride levels. (You are NOT what you eat.) The total intake of calories would be important to consider.
It seems counterintuitive until you think it through: if you deprive the body of carbs and limit protein and total energy intake, the body will break down triglycerides and other lipids to use for energy; if you flood the body with simple carbs, in excess, then de novo lipogenesis removes carbohydrates from the circulation and converts them into fatty acids, that are further converted into triglycerides or other lipids.
So a lower-calorie diet of mostly "good" fats (nuts, olives/olive oil, avocado, fatty fish, grass-fed meats and dairy, etc.) is potentially far healthier than a higher-calorie diet of mostly simple carbs. This may be true for those with obesity, diabetes and heart disease... and I see no reason why it might not also be true for those with certain cancers.
Farmers who raise beef understand the chemistry. To get the marbling in the tastiest steaks, the animals are finished off on feed lots where they eat corn & soy. Carb in, fat out.
Yet we continue to see food pyramids with carbs at the base & fats at the apex.
Many think that the heart-healthy Mediterranean diet must be low fat - but it is 40% fat.
-Patrick
Great analogy
Lupron and erleada cause me to gain 40 pounds maybe it's not all their fault but I was a muscular guy and we know that the no testosterone causes us to get and gain weight yeah are you guys that run 20 miles a day maybe not so so I should not take Lupron when that's what putting my cancer to sleep
Keep in mind that it is not just low T but the resulting low estrogen that brings bad changes. Low T is what helps us lose muscle, but it is mostly low E2 that is causing loss of bone density and the metabolic changes that bring weight gain and possible diabetes. You are stuck with the low T, but you can add back some E2 with low-dose patches.
There is excellent information in this video - at least enough to get me looking forward to the next one in the series. BE STRONG Y'ALL!!
