No CTCs/oligometastatic

[6357axbz]

If MDT eliminates all visible mets on a GA68 PSMA PET/CT scan and a CTC test is negative (I think that means no circulating micro-metastices). Is there a potential cure there?

[Tall_Allen]

No. It just means that the metastases are too small to be picked up on a PET scan, and cells are not spalling off from the tumors that are inevitably there. Think of detected metastases as just the visible part of your cancer.

[6357axbz in reply to Tall_Allen]

Thanks, I guess it’s good that whatever tumors exist they are not spalling off CTCs

[Hidden in reply to 6357axbz]

It’s great news👏🏼

[SPEEDYX in reply to Hidden]

Hey Scotty did you ever use a Spalding off the wall

[Hidden in reply to SPEEDYX]

I really don’t know shit about this technical stuff . Are you talking tennis balls or what? I’m lost in space??

[SPEEDYX in reply to Hidden]

Stickball....I know no walls out there..only mountain sides

[Fanger1]

Circulating Tumor Cells (CTCs) are another marker for pc patients. It's good to not have any detectable. Which test did you have?

[6357axbz in reply to Fanger1]

Analytical Method:

Immunomagnetic CTC Selection and Enumeration

Method Platform:

CellSearch CELLTRACKS AUTOPREP System

[Fanger1 in reply to 6357axbz]

Cell Search is FDA approved and finds CTCs that are Cytokeratin Positive (CK+). There are a few newer wet biopsy methods that are able to locate CTCs that are CK+ and CK-which you might consider having run. Please look into the Biocept CTC test. Good luck with keeping any CTCs on the run and practising social distancing! If you had a NO on your team that would be beneficial.

[tango65]

No, you can have metastases less than 4 mm and they will not be detected by the PSMA PET/CT scans. Having less than 5 CTC is a factor associated with better OS in patients with mCRPC initiating new chemotherapy treatment.

clincancerres.aacrjournals....

[6357axbz in reply to tango65]

Thanks Tango

[Hidden]

Cure is a BIG word, not to be used with stage #4 apc.. Nothing showing is great ! Congrats ... This is the odd psychology for us all . I’ve had no visible signs for almost five years now . I’m racked with the typical side effects of imrt and constant adt . I’ve had 3 T during this entire time .. Adjusting to life without t has its own set of charms . We should be happy you and I , that the beast is hiding for now . Stretch this out and live for the present . Good news. 🙏🏼

[6357axbz in reply to Hidden]

Here here Whimpy! Thanks

[Hidden in reply to 6357axbz]

Hang in there Sir!✌️😎