Metformin - A Cheap Diabetes Drug Shows Potential as a Life-Extension Therapy

[cesanon]

Myers had me on Metformin for off-label PCa purposes. Looks like it is good for all that ails you.

Important to note: the medical community isn’t convinced of the drug’s anti-aging benefits — and there’s a chance no one will conduct the human research needed to help them make up their minds, leaving metformin relegated to the realm of long-shot life-extension treatments.

Metformin has been in use as a diabetes treatment for decades, but in recent years, a number of researchers have started to explore whether the drug has additional health benefits.

A 2014 study concluded that diabetes patients taking the drug lived longer than a matched control group, leading the researchers to infer that metformin might benefit people without diabetes. A different study published the year prior determined that the drug could improve both the healthspan and lifespan of mice.

These and other studies led Poler and his Silicon Valley peers to seek prescriptions for metformin, which costs only about $0.05 per pill

Metformin - A Cheap Diabetes Drug Shows Potential as a Life-Extension Therapy

futurism.com/metformin-diab...

[Ralph1966]

What is the dosage you are takinf? I already have DM type 2 and taking 500 mg twice daily

[cesanon in reply to Ralph1966]

500mg extended release 4x per day.

[Ralph1966 in reply to cesanon]

So are you taking 500 mg every 6 hours? Or 1000 (2×500 mg) every

12 hours?

[cesanon in reply to Ralph1966]

2 every 12 hours

[Ralph1966 in reply to cesanon]

I will ask my PP if he can increase my dose to at least 500 mg X 3 or may be 1000 mg X 2 daily.

Thanks for your feedback

[Ralph1966]

Metformin and Berberine can work together against cancer:

Berberine seems to have so many benefits against cancer, well beyond its sugar control. But Metformin also has sugar controlling benefits and acts on AMPK - it is the ’diabetes drug’. For this reason, many users take an either/or approach. That seems to be quite wrong. Actually Berberine and Metformin seem to enhance each other’s activity. For example, there is a study with Non-Small Cell Lung Cancer (NSCLC) showing exactly that (12). They work together in vitro and in vivo against a particularly nasty cancer.

Dosage of Berberine in cancer therapy:

Berberine seems to be dose dependent and research indicates that low doses may be totally ineffective, and may even cause problems. The cancer inhibiting doses in research seem to start at 3 x 500 mg a day.

Berberine can cause a heavy heart beat and probably should not be taken long-term, although there is little evidence for this warning.

Berberine is, however, as powerful as pharmaceutical drugs. There are concerns about long-term usage causing metabolic changes. More work is however needed on this but warnings over long-term use persist.

canceractive.com/article/Be...