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New biopsy: now G4+3
I have been on AS followed by Behfar Ehdaie at MSK since 2020. PSA has been trending up with most recent being 6.1 Prior biopsy (2021) was G7 (3+4) with 3 positive cores out of ten. Two G6 and 1 G7 3+4 (with G4 in 2% of the core). MRI in January 2023 showed two lesions with PIRADS 3 (no EPE, no
I have been on AS followed by Behfar Ehdaie at MSK since 2020. PSA has been trending up with most recent being 6.1 Prior biopsy (2021) was G7 (3+4) with 3 positive cores out of ten. Two G6 and 1 G7 3+4 (with G4 in 2% of the core). MRI in January 2023 showed two lesions with PIRADS 3 (no EPE, no
rosenjpj
in
Prostate Cancer Network
1 year ago
Treatment Options PSA Increasing While on Lupron
I have been on intermittent ADT (Lupron/Eligard) from November 2018. During the last Lupron cycle my stopped going down. I got the first shot of this cycle in July, 2022 when my PSA was 0.56. By October it went down to 0.29 when got another shot. However, in January 2023 my PSA went up by a small amount
I have been on intermittent ADT (Lupron/Eligard) from November 2018. During the last Lupron cycle my stopped going down. I got the first shot of this cycle in July, 2022 when my PSA was 0.56. By October it went down to 0.29 when got another shot. However, in January 2023 my PSA went up by a small amount
dac500
in
Advanced Prostate Cancer
1 year ago
45 yr young. Next steps?
Gday All, thanks for support and response to previous post as there was Some really good info, contacts, recommendations shared with me that I did follow up on. One v interesting point of view, shared with me via zoom call recently from a renown respected Professor in my home country of Australia. He
Gday All, thanks for support and response to previous post as there was Some really good info, contacts, recommendations shared with me that I did follow up on. One v interesting point of view, shared with me via zoom call recently from a renown respected Professor in my home country of Australia. He
dochelem
in
Advanced Prostate Cancer
1 year ago
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PC drugs and Kidney Disease
My husband has kidney disease and I am wondering if any of you out that may also have kidney disease may know of any drugs we need to avoid regarding ADT? And/Or procedures? Thank you!
My husband has kidney disease and I am wondering if any of you out that may also have kidney disease may know of any drugs we need to avoid regarding ADT? And/Or procedures? Thank you!
USAFproudmom
in
Fight Prostate Cancer
1 year ago
Testosterone Recovery in Patients With Prostate Cancer Treated With Radiotherapy Plus ADT
https://www.urotoday.com/video-lectures/asco-gu-2023/video/mediaitem/3299-testosterone-recovery-in-patients-with-prostate-cancer-treated-with-radiotherapy-plus-adt-tanya-dorff.html?utm_source=newsletter_11544&utm_medium=email&utm_campaign=advanced-prostate-cancer-landscape-novel-therapies-and-precision-medicine-advancements
https://www.urotoday.com/video-lectures/asco-gu-2023/video/mediaitem/3299-testosterone-recovery-in-patients-with-prostate-cancer-treated-with-radiotherapy-plus-adt-tanya-dorff.html?utm_source=newsletter_11544&utm_medium=email&utm_campaign=advanced-prostate-cancer-landscape-novel-therapies-and-precision-medicine-advancements
SierraSix
in
Advanced Prostate Cancer
1 year ago
Time to saddle up the ADT pony
Its been a good 2+ yrs but my PSA has gone up to 2.5 so i go in next week for a PSMA scan and i would guess i will be back on ADT. So my issue is that I am taking all of my family to France in June and i remember how going on ADT the first time kicked my behind - and it was almost overnight. I hike
Its been a good 2+ yrs but my PSA has gone up to 2.5 so i go in next week for a PSMA scan and i would guess i will be back on ADT. So my issue is that I am taking all of my family to France in June and i remember how going on ADT the first time kicked my behind - and it was almost overnight. I hike
PabloK
in
Advanced Prostate Cancer
1 year ago
Semaglutide et al
I have never been obese (BMI >=30) but I have certainly been overweight (BMI>=25). There are many PCa papers associating "obesity" with poor survival. BMI is a surrogate for visceral adiposity (not always very accurate). Mortality risk with a BMI of 29 is presumably not much different than for a BMI
I have never been obese (BMI >=30) but I have certainly been overweight (BMI>=25). There are many PCa papers associating "obesity" with poor survival. BMI is a surrogate for visceral adiposity (not always very accurate). Mortality risk with a BMI of 29 is presumably not much different than for a BMI
pjoshea13
in
Fight Prostate Cancer
1 year ago
Consulting on next steps
As I am 10 months PSA undetectable and clear on basic bone scans I have started the process of consultation re staying on ADT (zoladex) and Apalutamide continuously or moving to intermittent (and what would that involve) or getting more treatment (J591 for example aimed at micromets). Following consult
As I am 10 months PSA undetectable and clear on basic bone scans I have started the process of consultation re staying on ADT (zoladex) and Apalutamide continuously or moving to intermittent (and what would that involve) or getting more treatment (J591 for example aimed at micromets). Following consult
Brysonal
in
Fight Prostate Cancer
1 year ago
T or E2
I'm reading a book by Dr Edward Friedman [i]The New Testosterone Treatment. [/i]I am finding it fascinating and confusing. He claims that the acting hormone for promoting Pca growth is estradiol and not testosterone at all. He makes a very convincing case for his claims. I'm trying to reconcile this
I'm reading a book by Dr Edward Friedman [i]The New Testosterone Treatment. [/i]I am finding it fascinating and confusing. He claims that the acting hormone for promoting Pca growth is estradiol and not testosterone at all. He makes a very convincing case for his claims. I'm trying to reconcile this
Burk
in
Fight Prostate Cancer
1 year ago
ART BCR Biochemical Recurrence post Radical Prostatectomy RP, Adjuvent Radiation Treatment, Benign Cells, usPSA Ultra Sensitive PSA
Some excerpts from a podcast covering many aspects of active surveillance, both post radical prostatectomy (RP) and adjuvant/ early salvage radiation (aRT / eSRT). There is an interesting breakdown of usPSA (ultra sensitive PSA) with predictive values for BCR. Last, it appears that the metric of ‘cure
Some excerpts from a podcast covering many aspects of active surveillance, both post radical prostatectomy (RP) and adjuvant/ early salvage radiation (aRT / eSRT). There is an interesting breakdown of usPSA (ultra sensitive PSA) with predictive values for BCR. Last, it appears that the metric of ‘cure
RMontana
in
Active Surveillance - Prostate Cancer
1 year ago
ADT and Testosterone Recovery
I found this recent study very interesting. https://www.urotoday.com/video-lectures/asco-gu-2023/video/mediaitem/3299-testosterone-recovery-in-patients-with-prostate-cancer-treated-with-radiotherapy-plus-adt-tanya-dorff.html I am 5 months into 24 months of ADT (Lupron) coupled with Radiation therapy
I found this recent study very interesting. https://www.urotoday.com/video-lectures/asco-gu-2023/video/mediaitem/3299-testosterone-recovery-in-patients-with-prostate-cancer-treated-with-radiotherapy-plus-adt-tanya-dorff.html I am 5 months into 24 months of ADT (Lupron) coupled with Radiation therapy
OldVTGuy
in
Prostate Cancer Network
1 year ago
Is Pluvitco about to become available soon?
Exhausted chemo, radiation therapy, ADT. Pluvitco would be my last chance of prolonging my life.
Exhausted chemo, radiation therapy, ADT. Pluvitco would be my last chance of prolonging my life.
p1411887
in
Advanced Prostate Cancer
1 year ago
On path for an MRI-guided SBRT
April 2023: After not too much activity on my side on this forum (aside from following a few threads), thought it time for a little update, as I am getting closer to a "definitive" therapy, after my initial diagnosis in Oct. 2019. In the last year or so, I have been doing imaging - PSMA PET-CT in March
April 2023: After not too much activity on my side on this forum (aside from following a few threads), thought it time for a little update, as I am getting closer to a "definitive" therapy, after my initial diagnosis in Oct. 2019. In the last year or so, I have been doing imaging - PSMA PET-CT in March
drmoose
in
Advanced Prostate Cancer
1 year ago
Fosfestrol ( oral Estrogen )/ Honvan for mCRPC progression ?
Complete case history in profile.
Current
therapy: ADT + Abiraterone + Pred PSA has gradually increase from a nadir of .7 in july 2022 to 4.5 in april -2023 Latest PSMA - Sclerotic lesions in left iliac bone and sacrum , showing increase tracer uptake - Low grade PSMA avid
Complete case history in profile.
Current
therapy: ADT + Abiraterone + Pred PSA has gradually increase from a nadir of .7 in july 2022 to 4.5 in april -2023 Latest PSMA - Sclerotic lesions in left iliac bone and sacrum , showing increase tracer uptake - Low grade PSMA avid
meowlicious99
in
Advanced Prostate Cancer
1 year ago
E2 Patch
I've been on ADT + Zytiga + Prednisone for 46 month's. In that time I've developed osteopenia, and have suffered an "Osteoporotic" compression fracture to the t11 vertebra, even though I've been receiving XGEVA, and taking Calcium Citrate, D3, and Multi vitamins as directed. I've read studies of e2
I've been on ADT + Zytiga + Prednisone for 46 month's. In that time I've developed osteopenia, and have suffered an "Osteoporotic" compression fracture to the t11 vertebra, even though I've been receiving XGEVA, and taking Calcium Citrate, D3, and Multi vitamins as directed. I've read studies of e2
Hidden
in
Advanced Prostate Cancer
1 year ago
How fast should your PSA drop after the first ADT treatment.
My husband has stage 4. It is in his lungs, ribs, shoulder and spine. Plus a lot of the lymph nodes. No pain except when he broke his ribs just lying on his stomach. That is healing without the palliative radiation. How fast should his PSA drop. How will we know if this is working. I know this treatment
My husband has stage 4. It is in his lungs, ribs, shoulder and spine. Plus a lot of the lymph nodes. No pain except when he broke his ribs just lying on his stomach. That is healing without the palliative radiation. How fast should his PSA drop. How will we know if this is working. I know this treatment
Bo1948
in
Advanced Prostate Cancer
1 year ago
Kidney Stones after ADT
I know that I don’t have advanced prostate cancer. Occasionally I’ll see a response to a question to the extent that if you don’t have advanced prostate cancer you don’t need to be on this site. I am very high risk and I’ve tried to find a site for me, but can’t seem to find one. So I’m going to go ahead
I know that I don’t have advanced prostate cancer. Occasionally I’ll see a response to a question to the extent that if you don’t have advanced prostate cancer you don’t need to be on this site. I am very high risk and I’ve tried to find a site for me, but can’t seem to find one. So I’m going to go ahead
Jack54
in
Advanced Prostate Cancer
1 year ago
It's Back - The Way Ahead
Here's my clinical history, diagnosed in Jan 14, Surgery in March 2014, BCR in Dec 15, SRT in Mar 16, taxotere, lupron and PLN IMRT starting in Jan 17 and now... Saint Luke’s Plarify 27 March 2023 FINDINGS: Physiologic distribution of tracer is seen in salivary glands, lacrimal glands, blood pool
Here's my clinical history, diagnosed in Jan 14, Surgery in March 2014, BCR in Dec 15, SRT in Mar 16, taxotere, lupron and PLN IMRT starting in Jan 17 and now... Saint Luke’s Plarify 27 March 2023 FINDINGS: Physiologic distribution of tracer is seen in salivary glands, lacrimal glands, blood pool
Hawk56
in
Advanced Prostate Cancer
1 year ago
EXTEND - Addition of Metastasis-Directed Therapy to Intermittent Hormone Therapy for Oligometastatic Prostate Cancer
The results of the EXTEND [EXTernal beam radiation to Eliminate Nominal metastatic Disease] Phase II Trial were published in JAMA Oncology this month [1]. {However, many will have seen the results, as presented at ASTRO 2022, & posted by Fish, 6 months ago [2].}
Results
"The study included
The results of the EXTEND [EXTernal beam radiation to Eliminate Nominal metastatic Disease] Phase II Trial were published in JAMA Oncology this month [1]. {However, many will have seen the results, as presented at ASTRO 2022, & posted by Fish, 6 months ago [2].}
Results
"The study included
pjoshea13
in
Fight Prostate Cancer
1 year ago
Follow up at Duke !!
not sure who, maybe Tall Allen, recommended Dr. Andrew Armstrong at Duke. He was charming, not rushed at all, had reviewed all our care up to this , our second opinion. He confirmed that PSMA PET is now SOC and would have been indicated prior to ADT. Also referenced the STAMPEDE info and affirmed that
not sure who, maybe Tall Allen, recommended Dr. Andrew Armstrong at Duke. He was charming, not rushed at all, had reviewed all our care up to this , our second opinion. He confirmed that PSMA PET is now SOC and would have been indicated prior to ADT. Also referenced the STAMPEDE info and affirmed that
warrior22
in
Advanced Prostate Cancer
1 year ago
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