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Any advice about future treatment?
Good morning sisters, I am at yet another crossroads and hoping for some advice. Diagnosed stage 4 high grade serous Jan 2020, had two surgeries, three courses of chemo (in total), short lived Niraparib, failed clinical trial (PICCOLO). So now having the 6th and final chemo of this third course ( Carboplatin
Good morning sisters, I am at yet another crossroads and hoping for some advice. Diagnosed stage 4 high grade serous Jan 2020, had two surgeries, three courses of chemo (in total), short lived Niraparib, failed clinical trial (PICCOLO). So now having the 6th and final chemo of this third course ( Carboplatin
Riverflo
in
My Ovacome
1 year ago
Calquence and mouth issues?
I’m wondering if anyone taking Calquence has experienced white patches in their mouth? My dentist noticed I have one on my tongue side of gums. It doesn’t hurt and can’t be scraped off (fits the description of leukoplakia when I Google). My dentist thought it looked like trauma and said to call if it
I’m wondering if anyone taking Calquence has experienced white patches in their mouth? My dentist noticed I have one on my tongue side of gums. It doesn’t hurt and can’t be scraped off (fits the description of leukoplakia when I Google). My dentist thought it looked like trauma and said to call if it
CoCoLuna11
in
CLL Support
2 years ago
To those who replied to my question on clinical trials
To those who replied to my question on joining clinical trials, I am overwhelmed by your kindness in sending me emails. I will answer your emails soon but I am currently recovering from a cataract operation and though my eyesight has improved a lot I still have difficulty reading and writing. Bear
To those who replied to my question on joining clinical trials, I am overwhelmed by your kindness in sending me emails. I will answer your emails soon but I am currently recovering from a cataract operation and though my eyesight has improved a lot I still have difficulty reading and writing. Bear
MyMiracle13
in
SHARE Metastatic Breast Cancer
1 year ago
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Effect of Melatonin Administration on Mitochondrial Activity and Oxidative Stress Markers in Patients with Parkinson's Disease 2021
Effect of Melatonin Administration on Mitochondrial Activity and Oxidative Stress Markers in Patients with Parkinson's Disease 2021
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8545577/ Abstract Mitochondrial dysfunction and oxidative stress are extensively linked to Parkinson's disease (PD)
Effect of Melatonin Administration on Mitochondrial Activity and Oxidative Stress Markers in Patients with Parkinson's Disease 2021
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8545577/ Abstract Mitochondrial dysfunction and oxidative stress are extensively linked to Parkinson's disease (PD)
Bolt_Upright
in
Cure Parkinson's
1 year ago
IVIG after heart surgery and stopping IBRUTIMIB
12 months ago I was on an Ibrutinib clinical trial for my CLL. Ibrutinib worked great for me for years. I found out I needed a triple bypass due to 95% LAD artery blockage. Not good! A stent wasn’t an option in my case due to necessity for blood thinners. Can’t do blood thinners, aspirin and Irbutinib
12 months ago I was on an Ibrutinib clinical trial for my CLL. Ibrutinib worked great for me for years. I found out I needed a triple bypass due to 95% LAD artery blockage. Not good! A stent wasn’t an option in my case due to necessity for blood thinners. Can’t do blood thinners, aspirin and Irbutinib
misterbee
in
CLL Support
1 year ago
My life …
so I have been struggling with PTSD, Depression and Anxiety. I can’t stop crying because of my teams. Does anyone have any ideas??
so I have been struggling with PTSD, Depression and Anxiety. I can’t stop crying because of my teams. Does anyone have any ideas??
Isturgglewithptsd
in
Anxiety and Depression Support
2 years ago
Volunteer Opportunity - Prostate Cancer Patient Advocate with SWOG for Genitourinary Cancer Committee
I have served as a volunteer Patient Advocate representing the LGBTQ+ Community with the Southwest Oncology Group (SWOG) for the past two years. As such I am serving as a member of the Patient Advocacy Committee (PAC) and the Diversity, Equality, and Inclusion Committee. I attend monthly zoom meetings
I have served as a volunteer Patient Advocate representing the LGBTQ+ Community with the Southwest Oncology Group (SWOG) for the past two years. As such I am serving as a member of the Patient Advocacy Committee (PAC) and the Diversity, Equality, and Inclusion Committee. I attend monthly zoom meetings
JRPnSD
in
Advanced Prostate Cancer
1 year ago
HAS ANYONE PARTICIPATED IN CLINICAL TRIALS
Hello everyone. Has anybody on this forum ever joined in a clinical trial? I have been invited to join a Phase 1 clinical trial for LOXO-783. The new drug is for those who have the PIK3CA mutation. At first I was very excited to join but when I was looking at the screening requirements, I don’t
Hello everyone. Has anybody on this forum ever joined in a clinical trial? I have been invited to join a Phase 1 clinical trial for LOXO-783. The new drug is for those who have the PIK3CA mutation. At first I was very excited to join but when I was looking at the screening requirements, I don’t
MyMiracle13
in
SHARE Metastatic Breast Cancer
1 year ago
response to clinical trial application?
A couple of months ago, I applied for a clinical trial that had just started recruiting. They are still recruiting and have begun administering the trial drug to participants. I never heard from trial staff. Has anyone applied for a trial and received notice whether they were rejected? Thank you. Sashay
A couple of months ago, I applied for a clinical trial that had just started recruiting. They are still recruiting and have begun administering the trial drug to participants. I never heard from trial staff. Has anyone applied for a trial and received notice whether they were rejected? Thank you. Sashay
Sashay2020
in
My Ovacome
1 year ago
Interesting video with active ongoing clinical trial. Maybe on option for some!!
https://www.urotoday.com/video-lectures/asco-2022/video/2853-the-future-of-radiopharmaceuticals-in-the-treatment-of-prostate-cancer-philip-kantoff.html
https://www.urotoday.com/video-lectures/asco-2022/video/2853-the-future-of-radiopharmaceuticals-in-the-treatment-of-prostate-cancer-philip-kantoff.html
Bkraus1
in
Advanced Prostate Cancer
1 year ago
More on the biomarker NFL
The identification of disease-modifying therapies is the Holy Grail of PD research, but to date no drug has been approved as such a therapy.1 There are numerous disease-modifying therapies currently in the pipeline attempting to modify the underlying pathomechanisms. In recent years, the results of
The identification of disease-modifying therapies is the Holy Grail of PD research, but to date no drug has been approved as such a therapy.1 There are numerous disease-modifying therapies currently in the pipeline attempting to modify the underlying pathomechanisms. In recent years, the results of
House2
in
Cure Parkinson's
1 year ago
Depression?
Hello. Two years into PMR journey. I am at 3mg pred and physically feel well. I am having bouts of severe depression and have never been depressed before. I am 59 years old and started menopause at 57 years old. Could it be a flare , adrenals or "the menopause"? Any info from the ladies would help
Hello. Two years into PMR journey. I am at 3mg pred and physically feel well. I am having bouts of severe depression and have never been depressed before. I am 59 years old and started menopause at 57 years old. Could it be a flare , adrenals or "the menopause"? Any info from the ladies would help
paleolady
in
PMRGCAuk
2 years ago
Annovis Bio Announces Approval for EU Clinical Trial Sites for the Phase 3 Study of Buntanetap for the Treatment of Parkinson's Disease
This trial is already open in the United States, and I believe some on this forum are participating. This announcemment indicates that the company is also opening clinical trial sites across the EU. I checked clnicaltrials.gov but they have not listed the EU sites yet. https://www.prnewswire.com/news-releases
This trial is already open in the United States, and I believe some on this forum are participating. This announcemment indicates that the company is also opening clinical trial sites across the EU. I checked clnicaltrials.gov but they have not listed the EU sites yet. https://www.prnewswire.com/news-releases
Canddy
in
Cure Parkinson's
1 year ago
“If Who is on First, What is on Second; No, He is on Third” (TTFD, Allithiamine, Fursultiamine)
TTFD is a B1 (Thiamine Tetrahydrofurfuryl Disulfide) The chemical Allithiamine (thiamine allyl disulfide or TAD) https://en.wikipedia.org/wiki/Allithiamine The product Allithiamine does not contain Allithiamine, it contains 50mg of TTFD https://www.walmart.com/ip/Allithiamine-Vitamin-B1-50-mg-250-Capsules-Ecological-Formulas
TTFD is a B1 (Thiamine Tetrahydrofurfuryl Disulfide) The chemical Allithiamine (thiamine allyl disulfide or TAD) https://en.wikipedia.org/wiki/Allithiamine The product Allithiamine does not contain Allithiamine, it contains 50mg of TTFD https://www.walmart.com/ip/Allithiamine-Vitamin-B1-50-mg-250-Capsules-Ecological-Formulas
Gcf51
in
Cure Parkinson's
2 years ago
Neuron23 Announces First-in-Human Dose in Phase 1 Clinical Trial of its Best-in-Class Brain-Penetrant LRRK2 Inhibitor for Parkinsons Disease
NEU-723 has been shown in preclinical studies to have strong disease-modifying potential with a higher therapeutic index than other candidates in development https://www.prnewswire.com/news-releases/neuron23-announces-first-in-human-dose-in-phase-1-clinical-trial-of-its-best-in-class-brain-penetrant-lrrk2
NEU-723 has been shown in preclinical studies to have strong disease-modifying potential with a higher therapeutic index than other candidates in development https://www.prnewswire.com/news-releases/neuron23-announces-first-in-human-dose-in-phase-1-clinical-trial-of-its-best-in-class-brain-penetrant-lrrk2
Farooqji
in
Cure Parkinson's
1 year ago
B12 levels
I thought it was my
clinical
depression
to blame and my meds have been increased. Dr says my B12 levels are ok and I don’t have to adjust the timing of 12 weeks. Still no better. Does anybody have any suggestions to why I’m still very tired.
I thought it was my
clinical
depression
to blame and my meds have been increased. Dr says my B12 levels are ok and I don’t have to adjust the timing of 12 weeks. Still no better. Does anybody have any suggestions to why I’m still very tired.
Diamonds_
in
Pernicious Anaemia Society
2 years ago
Athira announces clinical trials for Alzheimer’s, Parkinson’s, ALS treatments in 2023
https://www.healio.com/news/neurology/20230207/athira-announces-clinical-trials-for-alzheimers-parkinsons-als-treatments-in-2023
https://www.healio.com/news/neurology/20230207/athira-announces-clinical-trials-for-alzheimers-parkinsons-als-treatments-in-2023
Farooqji
in
Cure Parkinson's
1 year ago
📚 Research 101: Understanding the phases of a clinical trial
Clinical trials are conducted in phases. The trials at each phase have a different purpose and help scientists answer different questions: In the pre-clinical phase, researchers determine in a treatment or drug is safe and useful within a lab environment. In Phase I trials, researchers test a new
Clinical trials are conducted in phases. The trials at each phase have a different purpose and help scientists answer different questions: In the pre-clinical phase, researchers determine in a treatment or drug is safe and useful within a lab environment. In Phase I trials, researchers test a new
AnnaHU
HealthUnlocked
in
Research Opportunities
1 year ago
Besremi dosing research
It shows Besremi works better in 250-350-500 mcg in a month. [The response outcomes observed in multiple clinical trials of ropeginterferon alfa-2b confirm clinical benefits in MPN patients. Emerging data utilizing the 250-350-500 mcg regimen suggest that a higher initial dose with faster dose titration
It shows Besremi works better in 250-350-500 mcg in a month. [The response outcomes observed in multiple clinical trials of ropeginterferon alfa-2b confirm clinical benefits in MPN patients. Emerging data utilizing the 250-350-500 mcg regimen suggest that a higher initial dose with faster dose titration
Wennn
in
MPN Voice
1 year ago
Hi, everyoneI’m Esteer and I hope I can help and get the help snd support we all looking for in this site. I like to communicate with people
I suffered from depression, anxiety, OCD, post traumatic, I believe I’m an alcoholic. I really enjoy talking to people but sometimes… I can’t find anybody to talk to me. I don’t have many friends, being disappointed in life for a many people. So maybe that makes it hard to trust. But on the other side
I suffered from depression, anxiety, OCD, post traumatic, I believe I’m an alcoholic. I really enjoy talking to people but sometimes… I can’t find anybody to talk to me. I don’t have many friends, being disappointed in life for a many people. So maybe that makes it hard to trust. But on the other side
Estheer
in
Anxiety and Depression Support
2 years ago
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