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Hypothesis II
My hypothesis is that the antibody that attacks the intrinsic factor and or parietal cell may also bind to B12 rendering it unusable at the cellular level. That the production of the antibody with regards to amount is unknown and different at different times for the individual and different for each
My hypothesis is that the antibody that attacks the intrinsic factor and or parietal cell may also bind to B12 rendering it unusable at the cellular level. That the production of the antibody with regards to amount is unknown and different at different times for the individual and different for each
WIZARD6787
in
Pernicious Anaemia Society
6 months ago
Excellent explanation about B12 and malabsorption: may be due to other things besides pernicious anaemia
https://www.easy-immune-health.com/b12-malabsorption.html This article explains so well about B12 being malabsorbed; may not always be PA; could be H Pylori or other things. Explains everything really well. I have read: 'Could it be B12?' by Sally M. Pacholok and Jeffrey J. Stuart and it reflects similar
https://www.easy-immune-health.com/b12-malabsorption.html This article explains so well about B12 being malabsorbed; may not always be PA; could be H Pylori or other things. Explains everything really well. I have read: 'Could it be B12?' by Sally M. Pacholok and Jeffrey J. Stuart and it reflects similar
Hidden
in
Pernicious Anaemia Society
11 months ago
EPO and IV iron infusion
She is getting EPO injection once in two weeks to treat
anaemia
. She was given iron infusion shots (500 mg)two months back. She was feeling very energetic just after two weeks. Now her haemoglobin has again came down again.
She is getting EPO injection once in two weeks to treat
anaemia
. She was given iron infusion shots (500 mg)two months back. She was feeling very energetic just after two weeks. Now her haemoglobin has again came down again.
Mentoslfc
in
Kidney Disease
7 months ago
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ALS and B12
I ran across an article that was interesting, if for no other reason, for its quite detailed description of B12 deficiency. Scroll down to the heading, "Vitamin B12 levels and MND/ALS". https://jmedicalcasereports.biomedcentral.com/articles/10.1186/1752-1947-4-298
I ran across an article that was interesting, if for no other reason, for its quite detailed description of B12 deficiency. Scroll down to the heading, "Vitamin B12 levels and MND/ALS". https://jmedicalcasereports.biomedcentral.com/articles/10.1186/1752-1947-4-298
WiscGuy
in
Pernicious Anaemia Society
6 months ago
Undiagnosed Hashimotos update.
They ran more bloods, including, for pernicious
anaemia
, celiacs, and rheumatoid indicators.
They ran more bloods, including, for pernicious
anaemia
, celiacs, and rheumatoid indicators.
Rosieunwell
in
Thyroid UK
6 months ago
Iron profile
So these are my levels 6 weeks post iron infusion ,a combination of coming off the gabapentin and moving to pregablin I'm no longer depressed and able to function ,although my legs are still live they are no longer violent. Serum.iron ..22 Serum tibc 47 Iron transferrin sat 46.8 Serum ferritin 175
So these are my levels 6 weeks post iron infusion ,a combination of coming off the gabapentin and moving to pregablin I'm no longer depressed and able to function ,although my legs are still live they are no longer violent. Serum.iron ..22 Serum tibc 47 Iron transferrin sat 46.8 Serum ferritin 175
Baz33
in
Restless Legs Syndrome
6 months ago
yorkshiregirl4
I am thinking of arranging an appointment with a Neurologist but I am having great difficulty finding any Consultant who as an interest in Pernicious
Anaemia
.
I am thinking of arranging an appointment with a Neurologist but I am having great difficulty finding any Consultant who as an interest in Pernicious
Anaemia
.
yorkshiregirl4
in
Pernicious Anaemia Society
1 year ago
Shot in the Dark
I had iron deficient
anaemia
in 2020. Feel like I’m going mad!
I had iron deficient
anaemia
in 2020. Feel like I’m going mad!
marillo
in
Thyroid UK
6 months ago
medical records
It’s a bit basic but it takes me back to the 1970’s and shows I was first diagnosed with pernicious
anaemia
. I hope this is of some use. Best wishes x
It’s a bit basic but it takes me back to the 1970’s and shows I was first diagnosed with pernicious
anaemia
. I hope this is of some use. Best wishes x
Hedgehogs15
in
Pernicious Anaemia Society
7 months ago
Sitagliptin
Hi all Does anyone know if this medicine for type 2 diabetes has any effect on RLS/PLMD. I did a search and could not find it. I have been on 2 diabetic mecicines and both have sent my legs crazy or has other side effects. Thanks.
Hi all Does anyone know if this medicine for type 2 diabetes has any effect on RLS/PLMD. I did a search and could not find it. I have been on 2 diabetic mecicines and both have sent my legs crazy or has other side effects. Thanks.
CORFUORBUST
in
Restless Legs Syndrome
6 months ago
Bruxism, botulinum toxin, Hashimoto, anxiety, tension
I have had Hashimoto's Thyroiditis since 2014. I'm 34 years old. In addition I also have diabetes, PCOS and PTSD. I suffer from bruxism, a lot of anxiety, I live in a houve with children with autism. I broke my teeth and a dentist reconstructed them. Now I use dental plaque to sleep. But I still
I have had Hashimoto's Thyroiditis since 2014. I'm 34 years old. In addition I also have diabetes, PCOS and PTSD. I suffer from bruxism, a lot of anxiety, I live in a houve with children with autism. I broke my teeth and a dentist reconstructed them. Now I use dental plaque to sleep. But I still
Margimet
in
Thyroid UK
6 months ago
Iron deficiency problem? But told satisfactory . Please can anyone advise
Hi everyone, Hope you are all keeping well as we can be. Apologies for this long post I recently requested in Sep to have my VIT D levels checked as I recognised some of the symptoms from when I was deficient. And for some reason my levels had dropped so started 5 weeks ago to take a twice weekly
Hi everyone, Hope you are all keeping well as we can be. Apologies for this long post I recently requested in Sep to have my VIT D levels checked as I recognised some of the symptoms from when I was deficient. And for some reason my levels had dropped so started 5 weeks ago to take a twice weekly
PJDJ_08
in
Thyroid UK
6 months ago
Tinnatus
I see many people discussing the blood disorder aspect of Pernicious
Anaemia
but as yet have not seen many people who talk about the other problems it can cause! I have had, since being diagnosed with PA, terrible tinnatus.
I see many people discussing the blood disorder aspect of Pernicious
Anaemia
but as yet have not seen many people who talk about the other problems it can cause! I have had, since being diagnosed with PA, terrible tinnatus.
Akidma
in
Pernicious Anaemia Society
1 year ago
Non-Functional B12 Cellular Activity.
Non-Functional B12 Cellular Activity. A study posted by technoid. https://pure.tudelft.nl/ws/portalfiles/portal/153859755/Design_of_a_treatment_protocol_to_improve_the_health_of_B12_deficient_patients.pdf It is a study of the biochemistry of vitamin B12 cellular metabolism. 4 years of treating B12
Non-Functional B12 Cellular Activity. A study posted by technoid. https://pure.tudelft.nl/ws/portalfiles/portal/153859755/Design_of_a_treatment_protocol_to_improve_the_health_of_B12_deficient_patients.pdf It is a study of the biochemistry of vitamin B12 cellular metabolism. 4 years of treating B12
WIZARD6787
in
Pernicious Anaemia Society
6 months ago
High neutrophil count😱
My wife's last blood test showed her platelets were up at @800 And her neutrophil count at over 70, her Hgb was 116, hematocrit was 0.38 which is high for her, but as it was only three weeks since she had three units of packed red cells and a bag of iron, that was expected. I read in the guardian of
My wife's last blood test showed her platelets were up at @800 And her neutrophil count at over 70, her Hgb was 116, hematocrit was 0.38 which is high for her, but as it was only three weeks since she had three units of packed red cells and a bag of iron, that was expected. I read in the guardian of
jointpain
in
MPN Voice
6 months ago
Collapsed Identities
Pernicious
Anaemia
/vitamin B12 deficiency can be the basis of psychiatric symptoms and diagnoses and developmental disabilities. I am terribly sorry that my knowledge of the latter is limited.
Pernicious
Anaemia
/vitamin B12 deficiency can be the basis of psychiatric symptoms and diagnoses and developmental disabilities. I am terribly sorry that my knowledge of the latter is limited.
Narwhal10
in
Pernicious Anaemia Society
10 months ago
low iron and tremor
I have been tremoring for the last month and today my GP freaked out at my very low normal iron blood level. He said I eat meat so he can't understand why it's so low. Anyway, I checked with Google and low iron can cause tremors so I hope this is what is wrong and I will supplement with iron tablets
I have been tremoring for the last month and today my GP freaked out at my very low normal iron blood level. He said I eat meat so he can't understand why it's so low. Anyway, I checked with Google and low iron can cause tremors so I hope this is what is wrong and I will supplement with iron tablets
MEguy
in
Thyroid UK
6 months ago
Rapid responses to recent BMJ article
Thanks to Retteacherand LadyBothwellfor mentioning this article. I wondered if people had seen the rapid responses to the article. BMJ Vitamin B12 article Vitamin B12 BMJ 2023;383:e071725 https://www.bmj.com/content/383/bmj-2022-071725 Rapid Responses to above article https://www.bmj.com/content
Thanks to Retteacherand LadyBothwellfor mentioning this article. I wondered if people had seen the rapid responses to the article. BMJ Vitamin B12 article Vitamin B12 BMJ 2023;383:e071725 https://www.bmj.com/content/383/bmj-2022-071725 Rapid Responses to above article https://www.bmj.com/content
Sleepybunny
in
Pernicious Anaemia Society
6 months ago
From oxy to buprenorphine
I had my iron levels tested and all is good, not a candidate for infusion. Dr. Buchfuhrer suggested I switch from oxycodone to buprenorphine and tonight I did. Was nervous to go off of Oxy as it worked, but I noticed it was wearing off earlier and earlier. At 5 mg three times a day, I didn’t want
I had my iron levels tested and all is good, not a candidate for infusion. Dr. Buchfuhrer suggested I switch from oxycodone to buprenorphine and tonight I did. Was nervous to go off of Oxy as it worked, but I noticed it was wearing off earlier and earlier. At 5 mg three times a day, I didn’t want
Marlayna67
in
Restless Legs Syndrome
6 months ago
extreme fatigue
After two years of treatments for Pernicious
Anaemia
I still struggle with fatigue. I've been working out and riding a bike as much as energy levels allow me. I'd like to lift weights more but two days a week is all I can handle and need time to recover afterwards.
After two years of treatments for Pernicious
Anaemia
I still struggle with fatigue. I've been working out and riding a bike as much as energy levels allow me. I'd like to lift weights more but two days a week is all I can handle and need time to recover afterwards.
djrpdx
in
Pernicious Anaemia Society
2 days ago
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