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Xtandi
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What next after chemo?
I became mCRPC this March with rising PSA on Eligard and
xtandi
and then zytiga. I began chemo in June with docetaxil and carboplatin. PSA at start of chemo was 18. After 3 cycles, dropped to 10.6. After 5 cycles dropped to 7.5.
I became mCRPC this March with rising PSA on Eligard and
xtandi
and then zytiga. I began chemo in June with docetaxil and carboplatin. PSA at start of chemo was 18. After 3 cycles, dropped to 10.6. After 5 cycles dropped to 7.5.
Rexwaterbury
in
Advanced Prostate Cancer
5 years ago
Fatique
Good Morning Im currently on
Xtandi
and Firmagon, PSA down to 0.03..Had Radiation for 7 weeks a while ago. What advice is there for the daily fatique? Blessings
Good Morning Im currently on
Xtandi
and Firmagon, PSA down to 0.03..Had Radiation for 7 weeks a while ago. What advice is there for the daily fatique? Blessings
Andrevz
in
Advanced Prostate Cancer
5 years ago
Xtandi vs Erleada
Can someone explain the difference between Erleada and
xtandi
? My research doctor tells me they are chemically very close. So since I am currently on
xtandi
, Erleada is not an option.
Can someone explain the difference between Erleada and
xtandi
? My research doctor tells me they are chemically very close. So since I am currently on
xtandi
, Erleada is not an option.
Magnus1964
in
Advanced Prostate Cancer
5 years ago
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Second opinion at Cleveland Clinic... different treatment plan
So, after my dad's increases in PSA over three month periods (.07, .13, .23) his oncologist suggested we start with
Xtandi
and sent us to see an oncologist at the Cleveland main campus regarding Provenge. Well, insurance decided that they weren't going to cover
Xtandi
and said it's Zytiga for you!
So, after my dad's increases in PSA over three month periods (.07, .13, .23) his oncologist suggested we start with
Xtandi
and sent us to see an oncologist at the Cleveland main campus regarding Provenge. Well, insurance decided that they weren't going to cover
Xtandi
and said it's Zytiga for you!
Lynsi13
in
Advanced Prostate Cancer
5 years ago
Title Information
On Lupron then 3 years ago started
xtandi
, 1/201119 PSA is at 125 . Karmanos docter suggested a trial ESK981.with condition if it failed would get LU-177. It failed PSA went to740. Karmanos refused to give me the LU-177. PSA came down by itself to 370 When ESK failed.
On Lupron then 3 years ago started
xtandi
, 1/201119 PSA is at 125 . Karmanos docter suggested a trial ESK981.with condition if it failed would get LU-177. It failed PSA went to740. Karmanos refused to give me the LU-177. PSA came down by itself to 370 When ESK failed.
lewicki
in
Advanced Prostate Cancer
5 years ago
Scans look great, next step Provenge and holding off on 2nd line hormone therapies
She said that afterwards she does not want us to jump right in to a second line hormone treatment such as zytiga or
xtandi
but rather see how long he can benefit from lupron and provenge. Thoughts? I'm thrilled that his scans look good and that he qualifies for provenge!
She said that afterwards she does not want us to jump right in to a second line hormone treatment such as zytiga or
xtandi
but rather see how long he can benefit from lupron and provenge. Thoughts? I'm thrilled that his scans look good and that he qualifies for provenge!
Lynsi13
in
Advanced Prostate Cancer
5 years ago
Xtandi while on Chemo is working Well
This time Med Onc suggested we continue
Xtandi
, which had been used on a rechallenge basis after the prior 2 rounds of chemo, but NEVER during chemo. Results were impressive. PSA dropped from 2.8 to .5 with this combination.
Xtandi
on pure rechallenge basis had brought PSA down from 48 to 2.8.
This time Med Onc suggested we continue
Xtandi
, which had been used on a rechallenge basis after the prior 2 rounds of chemo, but NEVER during chemo. Results were impressive. PSA dropped from 2.8 to .5 with this combination.
Xtandi
on pure rechallenge basis had brought PSA down from 48 to 2.8.
vandy69
in
Advanced Prostate Cancer
5 years ago
No more <
Is there reason for concern that the
Xtandi
has started to fail after 21/2 years.
Is there reason for concern that the
Xtandi
has started to fail after 21/2 years.
rhome502
in
Advanced Prostate Cancer
5 years ago
enzalutamide (XTANDI®, Astellas Pharma Inc.) for patients with metastatic castration-sensitive prostate cancer (mCSPC).
On December 16, 2019, the Food and Drug Administration approved enzalutamide (
XTANDI
®, Astellas Pharma Inc.) for patients with metastatic castration-sensitive prostate cancer (mCSPC). FDA previously approved enzalutamide for patients with castration-resistant prostate cancer.
On December 16, 2019, the Food and Drug Administration approved enzalutamide (
XTANDI
®, Astellas Pharma Inc.) for patients with metastatic castration-sensitive prostate cancer (mCSPC). FDA previously approved enzalutamide for patients with castration-resistant prostate cancer.
Darryl
Partner
in
Advanced Prostate Cancer
4 years ago
How long are the 2nd generation drugs effective for? (2nd generation drugs I.e. Zytiga, Xtandi, appaludamide)
I have been told that the 2nd generation drugs (Zytiga,
Xtandi
& appaludamide) might only be effective for maybe 3 years. Is this true? Thank you for your opinion. Chris
I have been told that the 2nd generation drugs (Zytiga,
Xtandi
& appaludamide) might only be effective for maybe 3 years. Is this true? Thank you for your opinion. Chris
Christopherg
in
Advanced Prostate Cancer
5 years ago
just finished ext beam radiation to spine now on xofigo
zytiga quite working after 6 months mo psa up to 8.13 as of 9/1 mets in bones went from 4 to 10 Mo wanted me to start
xtandi
I refused so he sent me to a radiation oncologist who did a scan and seen a very bad met on a vertebrate thank was causing pain he hit with ext beam 5 times pain went away. next
zytiga quite working after 6 months mo psa up to 8.13 as of 9/1 mets in bones went from 4 to 10 Mo wanted me to start
xtandi
I refused so he sent me to a radiation oncologist who did a scan and seen a very bad met on a vertebrate thank was causing pain he hit with ext beam 5 times pain went away. next
Racer26
in
Advanced Prostate Cancer
5 years ago
Denied for Vision Trial
While we were waiting for all the tests, his PSA went up to 530.62 so the doctor prescribed him
Xtandi
(enzalutamide) . It seems like he has more energy now. But I'm really scared how long it will last..... Will you please let me know what option will we have after
Xtandi
fail on him?
While we were waiting for all the tests, his PSA went up to 530.62 so the doctor prescribed him
Xtandi
(enzalutamide) . It seems like he has more energy now. But I'm really scared how long it will last..... Will you please let me know what option will we have after
Xtandi
fail on him?
Muzpapa
in
Advanced Prostate Cancer
5 years ago
DO I GO WITH CHEMO OR ADT DRUGS?
The doc gave me a choice of chemo or the drugs such as Erleada,
Xtandi
or Zytiga. (I have read each drug results and am leaning towards Erleada?). His advice was to go to the drugs, the nurses advice was to go to chemo, saying there are better results with early chemo.
The doc gave me a choice of chemo or the drugs such as Erleada,
Xtandi
or Zytiga. (I have read each drug results and am leaning towards Erleada?). His advice was to go to the drugs, the nurses advice was to go to chemo, saying there are better results with early chemo.
EBFJ
in
Advanced Prostate Cancer
5 years ago
Xtandi and Firmagon side effect s
I had lab work after 9 days on
Xtandi
and my PSA is now going down instead of up. Anybody had these 2 drugs do that to them?
I had lab work after 9 days on
Xtandi
and my PSA is now going down instead of up. Anybody had these 2 drugs do that to them?
xpbdb
in
Advanced Prostate Cancer
5 years ago
Peanut butter bad??
Had great run on zytiga then on trial keytruda and
xtandi
. Failure 😖 he was diagnosed 8 years ago Gleason 8. Lymph node involvement. Treated with dr snuffy Meyers who then retired. Miss him. He is going for scans today just praying not in bones.
Had great run on zytiga then on trial keytruda and
xtandi
. Failure 😖 he was diagnosed 8 years ago Gleason 8. Lymph node involvement. Treated with dr snuffy Meyers who then retired. Miss him. He is going for scans today just praying not in bones.
Judymin
in
Advanced Prostate Cancer
5 years ago
Failing Clinical Trail
He failed
Xtandi
in 9 months, failed Erleada in 3 months.
He failed
Xtandi
in 9 months, failed Erleada in 3 months.
Hidden
in
Advanced Prostate Cancer
5 years ago
Xtandi is bringing PSA down ..will the cancer stop growing ?
Xtandi
49 days on
Xtandi
.. minimal side effects other than fatigue . PSA dropped from 22 to 18 in first 20 days and we expect it to decrease regularly month by month . Down side is Bone Scan shows the t10 is now significantly effected .
Xtandi
49 days on
Xtandi
.. minimal side effects other than fatigue . PSA dropped from 22 to 18 in first 20 days and we expect it to decrease regularly month by month . Down side is Bone Scan shows the t10 is now significantly effected .
Running-on-empty
in
Advanced Prostate Cancer
5 years ago
starting xtandia
Any suggestions for beginning
xtandi
after being on zytiga for 6 months?
Any suggestions for beginning
xtandi
after being on zytiga for 6 months?
linpisarn
in
Advanced Prostate Cancer
5 years ago
FDA approves Erleada for metastatic hormone-sensitive prostate cancer
Probably
Xtandi
too very soon. https://pcnrv.blogspot.com/2019/05/two-new-advanced-hormonal-agents.html
Probably
Xtandi
too very soon. https://pcnrv.blogspot.com/2019/05/two-new-advanced-hormonal-agents.html
Tall_Allen
in
Prostate Cancer Network
5 years ago
Optimal chemohormonal sequencing for metastatic castration-resistant prostate cancer MAY be Taxotere->Zytiga->Jevtana->Xtandi
Alternating chemos and hormonals like this seems to be optimal for metastatic castration-resistant prostate cancer (mCRPC). Other therapies may be able to be piggybacked so they can be tried sooner. https://pcnrv.blogspot.com/2019/12/optimal-chemohormonal-sequencing-for.html
Alternating chemos and hormonals like this seems to be optimal for metastatic castration-resistant prostate cancer (mCRPC). Other therapies may be able to be piggybacked so they can be tried sooner. https://pcnrv.blogspot.com/2019/12/optimal-chemohormonal-sequencing-for.html
Tall_Allen
in
Advanced Prostate Cancer
4 years ago
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